NIH

New look at atherosclerosis

Jul. 11, 2019—A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques.

Pediatric health conditions, their treatments and the related stress hinder the prefrontal cortex, which is the region of the brain associated with learning, memory and behavior. (istock)

Working memory in psychotic disorders

Jul. 11, 2019—Functional MRI studies have revealed that targeting activation of certain brain regions may improve working memory and cognition in psychotic disorders.

sad or anxious young white man sitting on front porch of apartment building with his hands clasped

Early detection of schizophrenia

Jun. 24, 2019—Inhibited temperament—a tendency to respond to novelty with wariness, fear or caution—may be a risk factor for schizophrenia that could be targeted for preventative interventions.

close-up of fish oil capsules in a glass bowl

Fish oil and cancer prevention

Jun. 24, 2019—Fish oil supplementation provides a modest but beneficial effect on reducing molecules associated with colorectal cancer development.

Schematic image of viruses, billions of which are estimated to enter the cells in your intestine every day. Recent experiments at Vanderbilt University indicate that genes in viruses of bacteria (Wolbachia) can transfer to or from animals, and some virus genes hijack insect sperm to cause an infertility at the forefront of mosquito control efforts.

Microbiome links diet to health

Jun. 20, 2019—Vanderbilt researchers have discovered that the gut microbiome composition modulates how dietary nutrients are metabolized, with potential downstream consequences on metabolic health.

Potential probe for early ovarian cancer

Jun. 20, 2019—Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme.

Steroid binding to metabolic enzyme

Jun. 12, 2019—Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.

Red telephone handset facing black telephone handset conceptualizing communication between the two

Cell-cell signals in developing heart

Jun. 10, 2019—Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease.

Close up of smiling African-American woman's mouth

Mouth health and colorectal cancer

Jun. 6, 2019—Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC.

Cardboard boxes on conveyor roller in distribution warehouse, Delivery and packaging service concept background. 3d illustration (Cardboard boxes on conveyor roller in distribution warehouse, Delivery and packaging service concept background. 3d illus

Study details regulation of a multi-drug transporter

May. 30, 2019—Vanderbilt University researchers have discovered how a protein pump distinguishes between chemicals that it will expel from a cell and inhibitors that block its action. The new findings could guide the development of more efficient inhibitors to prevent cancer cell resistance to chemotherapy.

Frog fungus fights back

May. 15, 2019—Louise Rollins-Smith and colleagues have discovered a new way that a deadly fungus evades frogs' immune systems.

Adhesive bandage holding together a splitting concrete wall. (Concept: termporary solution) Tight/shallow DOF on bandage.

Dynamic basement membranes

May. 9, 2019—Basement membranes are important structural and functional components of tissues. New research provides insight into how they repair themselves.