NIH
Relational memory in early psychosis
Sep. 10, 2019—Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis.
Astrocytes and epilepsy
Sep. 9, 2019—A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report.
How salt increases blood pressure
Sep. 5, 2019—Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension.
The plus and minus of microtubules
Sep. 5, 2019—Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer.
Chang, Englot receive $3M NIH grant for epilepsy imaging work
Aug. 29, 2019—A team led by an engineering professor who specializes in techniques to analyze functional neuroimaging data and a neurosurgeon-scientist has received a $3 million National Institutes of Health grant for epilepsy research.
A “rheostat” for cancer signals
Aug. 27, 2019—Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells.
Cancer susceptibility genes
Aug. 26, 2019—Gene variants associated with cancer risk appear to contribute to carcinogenesis by regulating target genes that in turn promote the generation of mutations.
How nerves may lose their insulation
Aug. 22, 2019—Vanderbilt’s Bruce Carter and colleagues have discovered how genetic changes in the protein PMP22 may contribute to a disease of peripheral nerves.
New prostate cancer treatment concept
Aug. 22, 2019—Combining immunotherapy and radiation therapy may be a powerful treatment approach for castration-resistant prostate cancer.
Host-microbe interactions in the gut
Aug. 13, 2019—Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health.
Pancreatic cancer clue
Aug. 12, 2019—Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer.
A probiotic treatment for obesity?
Aug. 8, 2019—Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases.