NIH Archives
Study finds unique form of chronic sinusitis in older patients
Jan. 18, 2019—Older patients with a diagnosis of chronic sinusitis have a unique inflammatory signature that may render them less responsive to steroid treatment, according to new research led by Justin Turner.
DNA’s on/off switch
Jan. 18, 2019—Walter Chazin and colleagues have identified how a chemical "switch" in DNA primase, an enzyme essential to the replication of our genomes, works in order to hand off genetic information to the next enzyme.
Signals from the “conveyor belt”
Jan. 18, 2019—Carlos Lopez, Tina Iverson and Vsevolod Gurevich propose that a conveyer belt best describes the mechanism by which cellular signals are handed off from enzyme to enzyme in the brain.
Building a pancreas
Jan. 17, 2019—Ken Lau and Guoqiang Gu have identified a critical biomarker in determining how a pancreatic progenitor cell will develop.
Research explores link between stem cell transplant, diabetes
Jan. 17, 2019—Brian Engelhardt is studying why as many as 50 percent of stem cell transplant recipients develop diabetes.
Pain relievers a risk for C. diff?
Jan. 17, 2019—David Aronoff and colleagues report an increased risk of the serious gastrointestinal infection C. diff following the use of NSAID pain relievers.
Trans-institutional team documents potential new treatment path for breast cancer
Jan. 16, 2019—A team led by biomolecular engineer John Wilson and cancer biologist Rebecca Cook have found a way to trigger an immune response that targets breast cancer cells.
Bile acids mediate metabolic benefits of weight-loss surgery
Jan. 10, 2019—A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signaling pathway in the positive metabolic effects of weight-loss surgery.
Breast cancer-killing RIG
Dec. 19, 2018—New research led by Rebecca Cook demonstrates that an antiviral receptor called RIG-I has potent immunogenic and therapeutic effects in breast cancer.
The exocyst dynamo
Dec. 14, 2018—Mukhtar Ahmed and colleagues say the methods they employed to understand the mechanisms by which exocysts--protein complexes essential to life--function have the potential to revolutionize our understanding of cell dynamics.
Study links soy formula feeding and menstrual pain
Dec. 13, 2018—The report authored by Margaret Adgent adds to the increasing evidence supporting the reproductive health consequences of early-life exposure to soy formula.
Discovery could lead to neutralizing West Nile virus
Dec. 7, 2018—Research led by James Crowe, Jr., could lead to the first effective treatment for this dangerous mosquito-transmitted infection.