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Study aims to predict treatment response in epilepsy patients

Mar. 14, 2019—Vanderbilt researchers are on a quest to develop early biomarkers of treatment outcomes for patients with temporal lobe epilepsy based on their individual brain networks.

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Reprogramming cells for kidney repair

Mar. 14, 2019—Lauren Woodard and Matthew Wilson have discovered a way to reprogram adult human kidney cells into cells similar to those that form during embryonic development, which could lead to new kidney disease treatments.

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Exploring the brain’s white matter

Mar. 14, 2019—Though neurological activity is generally associated with the brain's gray matter, Muwei Li and colleagues have now measured it in white matter as well.

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Correctly copying DNA

Mar. 14, 2019—New research into the enzyme topoisomerase II sheds light on how it helps DNA replicate properly.

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Novel DNA repair mechanism preserves genome integrity: study

Feb. 28, 2019—David Cortez and colleagues have discovered a new DNA repair mechanism.

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Personalized pain management

Feb. 28, 2019—People with low levels of endocannabinoids, which stimulate the same brain receptors turned on by the active ingredient in marijuana, experience greater pain relief from opioids than those with high levels.

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New biomaterial could improve bone grafting

Feb. 26, 2019—A new biomaterial-based bone graft extender created by Vanderbilt and U.S. Army researchers has the potential to improve treatment of critical orthopedic conditions.

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Skin diseases study uses crowdsourcing to gather data

Feb. 21, 2019—Identifying and quantifying skin lesions often requires hours of tedious visual inspection by experts, making it difficult to study a lot of them at once. Eric Tkaczyk and Daniel Fabbri have found that training multiple non-experts to do basic evaluations can achieve comparable results.

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Discovery of new “checkpoint” points to new cancer immunotherapy option

Feb. 21, 2019—An international team involving Vanderbilt researchers has discovered that a new “checkpoint” protein on immune system cells is active in tumors, and that blocking it — in combination with other treatments — is a successful therapeutic approach in mouse models of cancer.

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Adhesion protein optimizes border

Feb. 15, 2019—Matthew Tyska and colleagues have found that an adhesion protein in the gut is necessary for proper intestinal functioning.

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Modulating stress circuits

Feb. 15, 2019—Danny Winder and colleagues have demonstrated how norepinephrine and a stress factor call CRF interact, which may lead to new treatments for stress-related disorders.

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Probing H. pylori cancer protein

Feb. 15, 2019—Timothy Cover, john Loh and colleagues have identified how a certain type of mutation influences the risk of premalignant and malignant changes in the stomach.

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