NIH

Vanderbilt epidemiologists conducted in-depth whole genome sequencing of breast cancer risk genes in Black women, who die at higher rates and have more aggressive disease, to discover mutations that may improve testing and treatment selection. Read More

A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune disease and transplant rejection, Vanderbilt researchers discovered. Read More

New acquisition and reconstruction solutions for ultrasound imaging developed by a Vanderbilt team aim to fundamentally improve the ability to obtain high quality, clinically relevant images, especially in cases of heart disease. With a new, $2.3 million National Institutes of Health grant, the researchers will evaluate their advances on a specific subset of cardiac imaging... Read More

A biomedical engineering professor has received a $1.9 million NIH grant to investigate the effects of mechanical stimuli such as shear stress on the behavior of cancer cells in blood flow. J. Lawrence Wilson Professor Mike King and his research group will develop the devices for the study as well as new cell lines to... Read More

A biomedical engineering professor has received a $1.9 million NIH grant to investigate the effects of mechanical stimuli such as shear stress on the behavior of cancer cells in blood flow. J. Lawrence Wilson Professor Mike King and his research group will develop the devices for the study as well as new cell lines to... Read More

The billing codes in electronic health records are useful for counting skin cancers over time — an important metric for cancer risk assessment and prevention. Read More

Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy. Read More

The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered. Read More

Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease. Read More

Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction. Read More

Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report. Read More

Vanderbilt biochemists have discovered that the protein RADX has different biological effects at sites of DNA synthesis, depending on the cellular conditions — even though it works the same way in both stressed and unstressed cells. Read More

Hospital data from a CDC network that monitors influenza revealed that adults hospitalized for COVID-19 in the early months of the pandemic were 20x more likely to die compared to hospitalized influenza patients. Read More

Associate Professor of Nursing Laurie Connors has received a grant from the National Institutes of Health National Human Genome Research Institute to train doctoral nurses in the translation and integration of genomics into academics, research and clinical practice. Read More

Vanderbilt researchers find that heterosexually active Black males are the least likely to establish HIV care within one month of diagnosis and suggest that targeted interventions focus on this population. Read More

Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases. Read More

A multicenter study of ICU patients found that in the hospital, delirium was associated with a nearly three-fold increase in risk of death the following day, but after discharge there was no association between delirium and mortality. Read More

Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; Vanderbilt researchers have now identified genes and signaling pathways associated with the condition. Read More

A gene variant that lowers white blood cell levels and is common in individuals with African ancestry contributes to unnecessary bone marrow biopsies, according to a study published June 28 in JAMA Internal Medicine.  The findings, led by investigators at VUMC, are an example of how using genetic data could reduce a health disparity.  Read More

Exercise and movement may be a prescription to mitigate drug and alcohol seeking behavior due to its influence on the brain. Est. reading time: 3 mins. Read More