NIH
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ID of ‘stomach flu’ culprit
Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines. Read MoreAug 6, 2020
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The importance of estrogen cycles
Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer. Read MoreAug 6, 2020
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Post-transplant complication
Vanderbilt researchers conducted the largest analysis to date of a heart complication in children following stem cell transplant. The findings may help guide screening practices to improve outcomes. Read MoreJul 28, 2020
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Soy food, metabolism and the microbiome
Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered. Read MoreJul 27, 2020
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Stomach bug hit-and-run
The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate. Read MoreJul 23, 2020
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Cellular antiviral defenses
A cellular RNA quality control mechanism was known to restrict replication of RNA viruses. Vanderbilt researchers have discovered it is also antiviral against DNA viruses. Read MoreJul 23, 2020
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BME junior selected for inaugural NIH program to pursue biomedical graduate degree
Lucy Britto is one of six Vanderbilt undergraduates selected as a MARC scholar in the inaugural 2020 cohort of an innovative National Institutes of Health program. Read MoreJul 15, 2020
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Vanderbilt receives NIH award to enhance student diversity in biomedical sciences
Vanderbilt awarded NIH funds to establish the Maximizing Access to Research Careers (MARC) program to support diverse and research-focused undergraduates in biomedical sciences. Read MoreJul 14, 2020
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New tools to study bioactive lipids
Vanderbilt researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction. Read MoreJul 14, 2020
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“Nur” target may aid arthritis treatment
Vanderbilt immunologists have discovered that the protein Nur77 is part of a control mechanism that guards against autoimmunity in natural killer T cells. Read MoreJul 13, 2020
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Recurrent UTIs linked to hidden reservoir
Bacterial invasion of vaginal cells sets up a protective niche and a reservoir for recurrent urinary tract infections, Vanderbilt researchers demonstrated. Read MoreJul 9, 2020
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Keeping beta cells “fit”
Vanderbilt cell biologists are defining the factors that help beta cells in the pancreas stay healthy, secrete insulin and prevent diabetes initiation and progression. Read MoreJul 9, 2020
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VUMC-led network to focus on polygenic risk for common diseases
With the aid of a $75 million, five-year grant renewal, the Electronic Medical Records and Genomics Network (eMERGE) will venture beyond its current focus on monogenic disease to scoring research participants relative risk for complex heritable diseases such as cardiovascular disease, chronic kidney disease and type 2 diabetes. Read MoreJul 1, 2020
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Discovery of aggressive cancer cell types by Vanderbilt researchers made possible with machine learning techniques
Rebecca Ihrie and Jonathan Irish are leading the development of machine learning applications for brain cancer research. Read MoreJun 24, 2020
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A connection to schizophrenia
The insula, a small region of the brain involved in diverse brain functions had widespread dysconnectivity in schizophrenia, Vanderbilt researchers found. Read MoreJun 23, 2020
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Single mutation causes seizure disorder
A single mutation in one gene can impair inhibitory signaling in the brain and cause multiple types of seizures and behavioral abnormalities. Read MoreJun 22, 2020
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Probing DNA damage repair
After discovering a new mechanism for DNA damage repair last year, Vanderbilt biochemists now provide direct evidence for how it works. Read MoreJun 18, 2020
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Studying cells in reduced dimensions
Vanderbilt cell biologists have developed an unbiased, quantitative framework for evaluating single-cell data. Read MoreJun 18, 2020
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All of Us program launches cloud-based research platform
On May 27, the All of Us Research Program launched the beta version of its cloud-based research platform, the Researcher Workbench. Read MoreJun 18, 2020
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Robotic technology speeds arrhythmia gene classification
Vanderbilt University Medical Center investigators have used high-throughput robotic technology to rapidly study and classify variations in a gene linked to heart rhythm disorders and cardiac conditions. Read MoreJun 12, 2020