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NIH Archives

Study tracks incidence, timing of immunotherapy-related deaths

Sep. 13, 2018—Researchers led by melanoma researcher Douglas Johnson have answered questions about the incidence and timing of rare but sometimes fatal reactions to the most widely prescribed class of immunotherapies.

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Research reveals link between immunity, diabetes

Sep. 13, 2018—An immune cell called CD8+ is supposed to attack disease, but it can also contribute to inflammation, which can lead to insulin resistance and type 2 diabetes.

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Team’s findings could spur new treatments for type 2 diabetes

Sep. 6, 2018—New research by an international team that includes Vanderbilt researchers shows how a common diabetes drug blocks glucose production by the liver, suggesting new avenues for treatment.

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Immune system emerges as partner in opioid cravings fight

Sep. 5, 2018—There’s promise in specific immune system peptides—amino acid compounds that signal cells how to function. In this case, they may be affecting brain activity and, by extension, drug cravings.

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Team isolates antibodies that neutralize GI bug norovirus

Aug. 30, 2018—The discovery of these antibodies could significantly improve the diagnosis and treatment of the leading cause of stomach illness in the world.

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Investigators find that bile acids reduce cocaine reward

Aug. 30, 2018—The discovery that high levels of bile acids appear to blunt cravings for cocaine could lead to new treatments for addiction.

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Energetic gene switch

Aug. 30, 2018—James Galligan and Lawrence Marnett have discovered a new histone modification that can affect gene expression.

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High-speed atomic force microscopy reveals clock protein interactions

Aug. 20, 2018—Prof. Carl Johnson and his team discovered on-and-off interactions between KaiA and KaiC take only seconds but combine to create a 24-hour oscillation of phosphorylation in a test tube.

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Predictive models for gene regulation

Aug. 17, 2018—Modern statistical tools are not very accurate when it comes to predicting the discrete and non-symmetric behaviors of individual cells. Gregor Neuert and colleagues say that's because the wrong tools are being used.

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YAP after acute kidney injury

Aug. 17, 2018—ianchun Chen, Raymond Harris and colleagues have identified a potential new target for treating acute kidney injury.

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A new target for lung cancer

Aug. 17, 2018—Xiangming Ji, Pierre Massion and colleagues have discovered that blocking the transporter protein xCT could slow the progression of non-small cell lung cancer.

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Risk factors for faulty rhythms

Aug. 17, 2018—Prince Kannankeril and colleagues explored clinical and genetic factors associated with atrial tachycardia after congenital heart disease surgery in infants younger than 1 year old.

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