NIGMS

Cells in the back of the developing brain can give rise to brain tumors, suggesting they may be a target for treatment. Read More

The molecular structure of a protein involved in Alzheimer’s disease – and the surprising discovery that it binds cholesterol – could lead to new therapeutics for the memory-robbing disease. Read More

Enhancing stem cell survival is key to improving cell-based therapies for regenerative medicine, and a new drug could help. Read More

Vanderbilt-Ingram Cancer Center researchers have identified a new population of intestinal stem cells that may hold clues to the origin of colorectal cancer. Read More

New information about signaling pathways involved in colorectal cancer could aid in assessing prognosis and identifying new therapeutic targets for the disease. Read More

New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents. Read More

Vanderbilt researchers have discovered a new molecular participant in the Wnt signaling pathway, which plays important roles in cell growth, development and cancer. Read More

New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly. Read More

Wearing a nicotine patch may help improve memory loss in older adults with mild cognitive impairment, according to a study published this week by Paul Newhouse, director of the Center for Cognitive Medicine. Read More

About half of kidney patients will die from heart disease within five years of starting dialysis, yet patients with kidney failure are rarely included in heart disease research. Jorge Gamboa, M.D., T. Alp Ikizler, M.D., and Nancy Brown, M.D., completed a small study that suggests a more personalized approach to… Read More

Protein helps ensure proper division of chromosomes during cell division. Read More

Host cell protein may be a target for strategies to limit spread of virus-induced squamous cell cancers. Read More

Structural biology studies of a bacterial protein suggest a new target for treating life-threatening heart infection. Read More

Light and the hormone melatonin may play important roles in the developing brain. Read More

A protein critical in heart development may also play a part in colon cancer progression. Read More

Vanderbilt University investigators have discovered surprising new insights into the actions of NSAIDs. Read More

The antibiotics of the future could take a page from the immune system’s playbook – and “starve” bacteria of the nutrients they need. Read More

A regulatory loop in zebrafish may explain how the right and left sides of our brains take on different functions. Read More

Subtle genetic changes can have big effects on blood pressure while exercising. Read More