NCATS

MRI brain scans reveal that children with autism spectrum disorders respond to a narrower range of familiar rewards. Read More

Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling. Read More

A non-invasive measure of electrical brain activity in preterm infants predicts cognitive and communication functioning during early childhood, according to a new Vanderbilt University study. Read More

A team of engineers and doctors have developed a new wireless capsule that can give surgeons back their sense of touch when performing minimally invasive surgery. Read More

The nuclear receptor TR3 contributes to ovarian cancer cell death in response to platinum-based chemotherapy – and may be a good target for overcoming cell resistance to certain treatments. Read More

A biomarker for oxidative stress is elevated in patients with both autism spectrum disorder and gastrointestinal dysfunction, suggesting opportunities for individualized approaches to clinical care. Read More

A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer. Read More

A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder. Read More

Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat. Read More

A factor produced by most malignant cells can both promote and inhibit tumor growth – an insight that is critical to using cancer drugs developed to block this factor. Read More

Children with autism spectrum disorder are better at perceiving the motion of certain objects than are typically developing children their age. Read More

Vanderbilt researchers have developed a novel algorithm to improve results from proteomic studies. Read More

Eating fava beans increases dopamine in blood and urine, but does not stimulate urinary sodium excretion. Read More

Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy. Read More

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue. Read More

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen. Read More

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk. Read More

Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer. Read More

Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds. Read More

An inherited lung disease does not appear to have earlier onset and increased severity – a phenomenon called genetic anticipation – in successive generations. Read More