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NCATS Archives

Noninvasive test detects stomach bug

Aug. 12, 2013—A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer.

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Rhythm response tied to gene variant

Jun. 21, 2013—A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder.

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Studies outline new model for staph bone infections

Jun. 20, 2013—Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.

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Factor’s yin-yang tumor effects

Jun. 10, 2013—A factor produced by most malignant cells can both promote and inhibit tumor growth – an insight that is critical to using cancer drugs developed to block this factor.

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Autism speeds motion perception

Jun. 7, 2013—Children with autism spectrum disorder are better at perceiving the motion of certain objects than are typically developing children their age.

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Taking the ‘noise’ out of protein data

May. 1, 2013—Vanderbilt researchers have developed a novel algorithm to improve results from proteomic studies.

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Fava beans’ impact on urine sodium

Apr. 29, 2013—Eating fava beans increases dopamine in blood and urine, but does not stimulate urinary sodium excretion.

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A role for blood vessels in delirium?

Apr. 15, 2013—Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.

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Lung damage protector

Apr. 12, 2013—Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

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Acetaminophen: protective in sepsis?

Mar. 28, 2013—In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

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HDL cholesterol impaired in kidney disease

Jan. 21, 2013—HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

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A drug combo for ovarian cancer

Dec. 24, 2012—Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.

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