NCATS

  • Vanderbilt University

    Using billing codes to count cancers

    The billing codes in electronic health records are useful for counting skin cancers over time — an important metric for cancer risk assessment and prevention. Read More

    Sep. 2, 2021

  • COVID ICU

    Influenza network sizes up COVID

    Hospital data from a CDC network that monitors influenza revealed that adults hospitalized for COVID-19 in the early months of the pandemic were 20x more likely to die compared to hospitalized influenza patients. Read More

    Jul. 22, 2021

  • Digital illustration of heart in an x-ray of a human chest

    Heat for hypertension in autonomic failure

    Heat therapy could offer a novel nonpharmacologic approach for treating the overnight hypertension that affects patients with autonomic failure. Read More

    May. 25, 2021

  • fat cells

    HIV, diabetes and immune cells in fat

    In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes. Read More

    Mar. 18, 2021

  • Closeup shot of an African American man testing his blood sugar level

    Gene variant and glucose metabolism

    Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study. Read More

    Feb. 18, 2021

  • Up close photo of an electrocardiogram reading

    New clue to postural tachycardia

    Insight into the pathophysiology of an enigmatic and debilitating disease suggests new treatment approaches. Read More

    Feb. 4, 2021

  • Vanderbilt University

    Gene network for leukemia factor

    A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment. Read More

    Feb. 4, 2021

  • conceptual illustration of brain with tangled scribbles running through it

    Inflammation in genetic epilepsy

    Brain inflammation links genetic and acquired epilepsy — providing new clues about epilepsy development and pointing to potential treatments. Read More

    Jan. 21, 2021

  • arthritis

    Microbial RNA and rheumatoid arthritis

    Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases. Read More

    Jan. 11, 2021

  • An Aedes japonicu mosquito rest on the water surface from which it just emerged.

    Exploiting viral vulnerabilities

    The isolation of human monoclonal antibodies against dangerous viruses including EEEV, Hendra and Nipah could offer new ways to treat and prevent these infections. Read More

    Dec. 10, 2020

  • diabetes

    A cohort for type 2 diabetes studies

    A study group of more than 600,000 patients with type 2 diabetes, identified from electronic medical records in the PCORnet national research network, could be valuable for assessing the safety of type 2 diabetes drugs. Read More

    Nov. 17, 2020

  • Vanderbilt University

    Depression and the brain-age gap

    Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals. Read More

    Oct. 19, 2020

  • thalamus

    Pinpointing brain changes in psychosis

    Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment. Read More

    Oct. 1, 2020

  • Vanderbilt University

    Genes spell penicillin allergy risk

    Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction. Read More

    Oct. 1, 2020

  • New mother smiling and holding newborn baby at home

    Fibroids and birth outcomes

    Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance. Read More

    Sep. 8, 2020

  • An injectable drug (heroin) is loaded into a syringe while prescription medication is strewn about haphazardly.

    Land of plenty (of opioids)

    Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction. Read More

    Aug. 24, 2020

  • Vanderbilt University

    ID of ‘stomach flu’ culprit

    Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines. Read More

    Aug. 6, 2020

  • schizophrenia

    A connection to schizophrenia

    The insula, a small region of the brain involved in diverse brain functions had widespread dysconnectivity in schizophrenia, Vanderbilt researchers found. Read More

    Jun. 23, 2020

  • The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver, and gallbladder).

    Transporter’s role in gut barrier

    A disease-associated mutation in a transporter protein impairs gut barrier function, leading to gastrointestinal disease and chronic infections. Read More

    Apr. 21, 2020

  • illustration of head dissolving into pixels

    Damage, disruption, delirium

    New findings suggest that treatments that decrease oxidative damage might help with postoperative delirium that occurs in up to 30% of cardiac surgery patients. Read More

    Apr. 20, 2020