NCATS

Vanderbilt researchers have developed a high-throughput assay that will aid in identifying new compounds to treat preterm labor or postpartum bleeding. Read More

A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, Vanderbilt University investigators have discovered. Read More

Thirty-three percent of pediatric heart transplant patients developed antibodies against the donor heart, which can lead to rejection, a new Vanderbilt study reports. Read More

Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution. Read More

Treatment for congenital heart disease during infancy may result in cognitive and attentional deficits during adolescence and young adulthood, Vanderbilt researchers have found. Read More

The timing of folic acid-containing prescription filling during pregnancy was associated with childhood asthma, according to a new Vanderbilt study. Read More

Drugs that inhibit the Wnt signaling pathway can regenerate injured skin and may be useful in treating fibromatosis, degenerative joint disease and cancer. Read More

Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions. Read More

Vanderbilt researchers have discovered how certain molecules with antibiotic properties are synthesized, findings that could lead to new drugs that overcome the increased antibiotic resistance in bacteria. Read More

Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action. Read More

Vanderbilt investigators report the first use of a specialized type of MRI to study the hippocampus in patients with schizophrenia. Read More

Inhibitors of the enzyme phospholipase D1 suppress the replication of HIV-1, Vanderbilt investigators have discovered. Read More

Vanderbilt researchers have discovered a novel mechanism for the development of dendritic spines – sites of nerve cell communication. Read More

New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas. Read More

Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts. Read More

New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease. Read More

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist. Read More

Alterations of the vestibular system - the part of our inner ear that controls balance - may contribute to bone loss related to both aging and space travel. Read More

Patients with orthostatic intolerance – problems when standing – have cognitive changes, even when seated, compared to healthy individuals. Read More

Growing evidence suggests that fish oil, thought to directly prevent inflammation, oxidative stress and heart disease, may have limited clinical utility. Read More