NCATS

Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders. Read More

Brain imaging studies have implicated the connection between two brain regions in the pathophysiology of schizophrenia. Read More

Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found. Read More

Vanderbilt investigators have discovered a role for immune system T cells in slowing the decline in skeletal muscle function in patients with Duchenne muscular dystrophy. Read More

Studies of alpha-B crystallin in zebrafish could ultimately lead to improved treatment for cataracts and heart disease. Read More

Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered. Read More

The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years. Read More

Automated techniques can assist in understanding and managing growing volumes of messages sent through secure patient portals, Vanderbilt researchers found. Read More

Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer. Read More

Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension. Read More

A noninvasive MRI technique may help predict a troubling side effect of common medications for Parkinson’s Disease and improve clinical treatment plans. Read More

Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered. Read More

With other risk factors held equal, children who received a benzodiazepine sedative drug were nearly three times more likely to experience delirium – confused thought – the following day. Read More

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy. Read More

A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage. Read More

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies. Read More

Signaling through a complex of proteins called mTORC2 plays a role in breast cancer migration, invasion and metastasis, Vanderbilt researchers reported. Read More

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition. Read More

RSV infection reduces the risk of infection with human rhinovirus, which could have implications for vaccine development and prevention strategies for viral respiratory tract infections in infants. Read More

Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension. Read More