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Hassane Mchaourab

Study details regulation of a multi-drug transporter

May. 30, 2019—Vanderbilt University researchers have discovered how a protein pump distinguishes between chemicals that it will expel from a cell and inhibitors that block its action. The new findings could guide the development of more efficient inhibitors to prevent cancer cell resistance to chemotherapy.

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Fueling the MATE transporter

Jul. 20, 2018—In new research, Hassane Mchaourab and colleagues have uncovered new insights into drug resistance that could lead to the development of new anti-cancer and antibacterial drugs.

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Faculty meeting recognizes excellence in education, research and clinical service

May. 24, 2018—During Wednesday’s Spring Faculty Meeting, Jeff Balser, M.D., Ph.D., dean of Vanderbilt University School of Medicine and President and CEO of Vanderbilt University Medical Center, highlighted the medical school’s rising stature among the country’s top-tier institutions.

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A cataract-heart connection

Jan. 25, 2018—Studies of alpha-B crystallin in zebrafish could ultimately lead to improved treatment for cataracts and heart disease.

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Study catches ‘notorious’ drug pump in action

Mar. 16, 2017—Researchers at Vanderbilt University Medical Center (VUMC) have mapped the conformational changes that occur in a protein “notorious” for pumping chemotherapeutic drugs out of cancer cells and blocking medications from reaching the central nervous system.

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Membrane fats impact drug transporter

Jul. 14, 2016—New studies of a membrane transporter could explain antibiotic resistance – and lead to novel ways to combat it.

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Dynamics of a drug resistance transporter

Feb. 5, 2016—Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance.

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Grad students welcome at Oct. 14 forum discussing graduate education at VU

Oct. 8, 2015—The purpose of the event is to capture feedback on the proposals of the Graduate Education Study Group’s executive summary from current graduate students.

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Next graduate education forum is Oct. 5

Sep. 30, 2015—The third in a series of forums discussing graduate education at Vanderbilt is scheduled for Monday, Oct. 5, from 4 to 5 p.m. in the Student Life Center Board of Trust Room.

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Next graduate education forum set for Sept. 24

Sep. 21, 2015—The second in a series of forums discussing graduate education at Vanderbilt is scheduled for Thursday, Sept. 24.

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In a zebrafish’s eye

Jul. 29, 2015—Vanderbilt investigators demonstrate that a certain eye lens protein is evolutionarily conserved between zebrafish and rat, suggesting that zebrafish can be used as a model system to understand eye lens disorders such as cataracts.

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New view of transporter dynamics

Oct. 23, 2014—New insights to the workings of a protein that moves neurotransmitters across the nerve cell membrane could aid the design of more effective antidepressants.

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