Department Of Veterans Affairs
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Genetics of lung cancer survival
Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans. Read MoreJun 29, 2017
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VUMC team’s discovery could lead to new diabetes treatment
High circulating glucose, the hallmark of diabetes, is linked to the disease’s most serious complications including heart disease, kidney failure, blindness and amputation. Diabetes is the sixth leading cause of death and costs the nation an estimated $322 billion a year. Restoring the action of insulin has been the traditional… Read MoreJun 15, 2017
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Veterans Affairs Research Conference
The 3rd National Veterans Health Affairs Research Conference held at Vanderbilt University Medical Center May 17-18. Read MoreJun 1, 2017
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EETs contribute to insulin sensitivity
Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension. Read MoreMay 11, 2017
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Richmond to speak at national VA research conference on cancer immunotherapy
Vanderbilt University cancer researcher Ann Richmond, Ph.D., 2016 recipient of one of the highest honors for scientific achievement bestowed by the U.S. Department of Veterans Affairs, will be a keynote speaker during a national VA research conference next week at Vanderbilt University School of Medicine. Read MoreMay 11, 2017
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Therapeutic targets for diabetes
Vanderbilt investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes. Read MoreMay 3, 2017
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Delirium in the ED
Interventions for delirium in the emergency department setting are needed to preserve patients’ long-term function and cognition, Vanderbilt investigators have found. Read MoreMar 20, 2017
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New target for colorectal cancer
Vanderbilt investigators have discovered that activated epidermal growth factor receptor may be a target for therapies to prevent colorectal cancer development. Read MoreMar 17, 2017
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Esophageal cancer complexities
New findings that reveal complex interactions in esophageal adenocarcinoma could lead to diagnostic, prognostic or therapeutic biomarkers. Read MoreMar 16, 2017
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Organ-on-a-chip mimics heart’s biomechanical properties
Scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart’s amazing biomechanical properties in order to study cardiac disease, develop heart drugs. Read MoreFeb 22, 2017
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Improving therapies for GI tumors
A signaling protein overexpressed in upper gastrointestinal cancers is an attractive therapeutic target. Read MoreFeb 20, 2017
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Improving wound healing
Vanderbilt researchers have shown that an injectable material improves wound healing and may be useful for large skin wounds such as those in patients with diabetes. Read MoreNov 8, 2016
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VUMC investigators find pathogens work together to infect host
Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection. Read MoreNov 3, 2016
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VA honors Richmond’s scientific contributions
Vanderbilt University cancer researcher Ann Richmond, Ph.D., has won the 2016 William S. Middleton Award, the highest honor for scientific achievement bestowed by the Biomedical Laboratory Research and Development Service of the U.S. Department of Veterans Affairs (VA). Read MoreOct 6, 2016
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In search of new asthma therapies
A peptide molecule relaxes airway smooth muscle and may be a potential therapeutic for asthma that has become resistant to standard therapies. Read MoreAug 15, 2016
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Superior scan for tumors
Imaging with a compound that binds to neuroendocrine cells is a safer and more effective way to detect rare neuroendocrine tumors. Read MoreJun 24, 2016
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It takes two to tango: beta cell development
Defining the genes required for the function of insulin-producing beta cells is crucial for ongoing efforts to develop a cell-based therapy for diabetes. Read MoreJun 23, 2016
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How strep grabs on to platelets
New structural details of the binding of the bacterium Streptococcus sanguinis to platelets may offer new therapeutics for life-threatening cardiovascular infections. Read MoreApr 20, 2016
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Switching breast cancer off
Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets. Read MoreApr 14, 2016
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Immune defenses in asthma
Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease. Read MoreApr 5, 2016