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Department of Veterans Affairs Archives

Target for inflammatory bowel disease

Mar. 1, 2013—The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.

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Do-it-yourself repair in the kidney

Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.

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Genetic clues to lung scarring

Dec. 10, 2012—A rare genetic syndrome provides new clues to lung scarring (pulmonary fibrosis), a potentially deadly consequence of many lung diseases.

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More gene links to breast cancer risk

Oct. 19, 2012—Two newly identified gene variants linked to breast cancer may aid in predicting disease risk and targeting screening and prevention strategies.

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Target acquired for aggressive tumor

Sep. 27, 2012—New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified.

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Targeting new pathways to ease pain

Aug. 30, 2012—The spinal cord’s neuropeptide Y signaling pathway may be a good target for new pain therapeutics.

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Gene linked to familial prostate cancer

Aug. 23, 2012—A rare, inherited mutation confers an eightfold increased risk of prostate cancer, a recent study shows.

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Long live the therapeutic stem cells

May. 17, 2012—Enhancing stem cell survival is key to improving cell-based therapies for regenerative medicine, and a new drug could help.

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Pathways to delirium in the ICU

Apr. 17, 2012—Study suggests that the “kynurenine” biochemical pathway could be a target for reducing delirium and coma in critically ill patients.

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Plant compound quells inflammation

Apr. 6, 2012—Berberine, an herbal remedy for diarrhea and intestinal parasites, may be an effective treatment for gastrointestinal inflammatory diseases.

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Smoking stokes cells’ cancer capacity

Mar. 23, 2012—Cellular pathways altered by chronic exposure to cigarette smoke may reveal new biomarkers to assess smoking-induced lung cancer risk.

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Obesity turns “good” cholesterol bad

Mar. 21, 2012—Studies offer new insights into how obesity impairs the function of HDL, the “good” cholesterol.

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