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Department of Veterans Affairs Archives

Increased cell permeability may protect from colitis

Apr. 25, 2014—Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation.

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Delirium increases long-term disability

Mar. 17, 2014—Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge.

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Probing the pathogenesis of leukemia

Feb. 27, 2014—A new mouse model reveals gene clusters important in a treatment-resistant form of leukemia.

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New direction for treating lung cancer

Feb. 7, 2014—Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer.

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Is healthy obesity possible?

Jan. 29, 2014—It might be possible to generate a “metabolically healthy” state of obesity by targeting signaling pathways that improve insulin sensitivity.

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Searching for beta cell stimulators

Jan. 13, 2014—Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes.

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Therapeutic target for gastric cancer

Dec. 12, 2013—A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.

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Therapeutic target for synovial sarcoma

Nov. 21, 2013—Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer.

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VUCast: Startling brain-related study on critically ill patients

Oct. 16, 2013—In the latest VUCast: ICU patients are leaving hospitals with a dementia-like disease; What’s the fate of the Republican Party?; Hear from Pulitzer Prize-winning author and Distinguished Visiting Professor Jon Meacham; and It's time to celebrate -- the Rate My Professor 2013 rankings are in. All this and more in Vanderbilt’s online newscast. Watch now.

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Cell changes en route to stomach cancer

Sep. 26, 2013—Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer.

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Factor’s yin-yang tumor effects

Jun. 10, 2013—A factor produced by most malignant cells can both promote and inhibit tumor growth – an insight that is critical to using cancer drugs developed to block this factor.

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Salt revs stomach bug’s cancer impact

May. 13, 2013—A high-salt diet worsens the carcinogenic effects of Helicobacter pylori, a bacterium that colonizes the stomachs of half of the world’s population.

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