Department Of Veterans Affairs

Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer. Read More

Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor. Read More

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered. Read More

Lauren Woodard and Matthew Wilson have discovered a way to reprogram adult human kidney cells into cells similar to those that form during embryonic development, which could lead to new kidney disease treatments. Read More

Identifying and quantifying skin lesions often requires hours of tedious visual inspection by experts, making it difficult to study a lot of them at once. Eric Tkaczyk and Daniel Fabbri have found that training multiple non-experts to do basic evaluations can achieve comparable results. Read More

Timothy Cover, john Loh and colleagues have identified how a certain type of mutation influences the risk of premalignant and malignant changes in the stomach. Read More

Researchers at Vanderbilt University Medical Center have identified a biomarker for insulin-producing beta cells. Their finding could lead to improved ways to study and treat diabetes. Read More

New research by Jonathan Lehman and Pierre Massion have identfied a bioimarker that suggests poor prognosis for small-cell lung cancer, as well as potential target for new therapies. Read More

Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis. Read More

The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read More

Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention. Read More

The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered. Read More

New research reveals a unique mechanism of C. difficile toxin neutralization by a monoclonal antibody, suggesting new therapeutic approaches. Read More

New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition. Read More

Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies. Read More

New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines. Read More

Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”). Read More

Facilitated reporting of medication-related events in the intensive care unit can provide opportunities for optimizing quality of care and patient safety. Read More

Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer. Read More

Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers. Read More