Department Of Veterans Affairs

  • Vanderbilt University

    Beta cell regeneration

    Vanderbilt researchers dissected the complex microenvironment of the pancreatic islet to discover the signals that drive beta cell regeneration — as a possible treatment for diabetes. Read More

    May 20, 2021

  • doctor checking patient's blood pressure

    Genetic ancestry and hypertension risk

    Racial disparities in hypertension risk are due in part to genetic differences between ancestries, Vanderbilt investigators find in a study of participants in the Million Veteran Program. Read More

    Apr 29, 2021

  • Human kidney cross section on scientific background. 3d illustration

    New insights into kidney development

    Integrin-linked kinase, a central component of a complex that coordinates cell signaling involved in migration, proliferation and cell death, plays a role in kidney development and epithelial cell function. Read More

    Apr 15, 2021

  • Vanderbilt University

    Study revises understanding of cancer metabolism

    Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years. Read More

    Apr 7, 2021

  • white pills spilling out of a prescription bottle

    Codeine metabolizer status in clinical practice

    Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine. Read More

    Apr 5, 2021

  • Vanderbilt University

    Targeting glucagon action in diabetes

    Disrupting the action of glucagon — a pancreatic hormone that works to raise blood glucose — restores functional insulin-producing cells in mouse models of type 1 diabetes and may be a promising treatment strategy. Read More

    Mar 4, 2021

  • arthritis

    Microbial RNA and rheumatoid arthritis

    Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases. Read More

    Jan 11, 2021

  • Digital illustration of heart in an x-ray of a human chest

    Polymer protection for heart muscle

    Vanderbilt researchers demonstrate that the polymer P188 has promise as a therapy to prevent reperfusion injury — the cellular damage that occurs when blood flow returns after an ischemic event like a heart attack. Read More

    Dec 14, 2020

  • diabetes

    A cohort for type 2 diabetes studies

    A study group of more than 600,000 patients with type 2 diabetes, identified from electronic medical records in the PCORnet national research network, could be valuable for assessing the safety of type 2 diabetes drugs. Read More

    Nov 17, 2020

  • x-ray of lungs with a suspicious spot highlighted in red

    New therapeutic target for lung cancer

    Vanderbilt researchers have identified a new molecular partner — and potential therapeutic target — in a signaling axis that drives lung cancer. Read More

    Nov 12, 2020

  • Vanderbilt University

    Clue to diabetic kidney disease

    Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication. Read More

    Oct 5, 2020

  • Vanderbilt University

    Rational vaccine design

    Understanding immunity generated by smallpox vaccine may hold lessons for COVID-19 vaccine development. Read More

    Sep 22, 2020

  • close up of blood vessels

    A “torque” for tumor blood vessels

    Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies. Read More

    Aug 20, 2020

  • metastatic melanoma

    A potential new targeted therapy for metastatic melanoma

    While 60 percent of people with metastatic melanoma, an aggressive type of skin cancer, have multiple treatment options available to them, roughly 40 percent either do not respond to treatment, or relapse. Read More

    Aug 19, 2020

  • Helicobacter Pylori bacterium, medical illustration pathogenic microorganism in human stomach

    Stomach bug hit-and-run

    The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate. Read More

    Jul 23, 2020

  • arthritis

    “Nur” target may aid arthritis treatment

    Vanderbilt immunologists have discovered that the protein Nur77 is part of a control mechanism that guards against autoimmunity in natural killer T cells. Read More

    Jul 13, 2020

  • Human kidney cross section on scientific background. 3d illustration

    Protecting the injured kidney

    Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it. Read More

    Jun 4, 2020

  • Vanderbilt Divinity School new addition (Vanderbilt University)

    Vanderbilt Divinity and VA partner on doctor of ministry for chaplains

    A new partnership between the Divinity School and Mental Health and Chaplaincy, a national program of the Veterans Health Administration, will relaunch a doctor of ministry program at Vanderbilt. Read More

    Mar 6, 2020

  • Yawning newborn caucasian baby.

    Clues to lung injury in preterm babies

    Jennifer Sucre and colleagues have discovered a factor that contributes to the pathological changes of bronchopulmonary dysplasia, the most common complication of preterm birth. Read More

    Mar 5, 2020

  • Helicobacter Pylori bacterium, medical illustration pathogenic microorganism in human stomach

    Powering H. pylori pathogenesis

    Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer. Read More

    Feb 6, 2020