Craig Lindsley
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New drug candidates targeting blood clots developed through computer-aided drug design
Using computer-aided drug design, Heidi Hamm, Craig Lindsley, and Jens Meiler and their labs generated a novel series of biologically active compounds that can serve as a basis for anti–blood clot preventative drugs. Read MoreJun 11, 2024
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Discovery Vanderbilt sends research soaring
On October 17, 2022, Vanderbilt University launched “Discovery Vanderbilt” to embolden faculty, students and staff to pursue innovative ideas through disciplined, rigorous inquiry. Led by Provost Cybele Raver, the university committed $80 million in the effort—and invested $50 million in the first year alone. Read MoreApr 15, 2024
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Watch now: Lab-to-Table Conversation: Beyond Addiction: Therapeutic Developments and Societal Impact
Join the next Lab-to-Table conversation, “Beyond Addiction: Therapeutic Developments and Societal Impact” on Jan. 24 at 11:30 a.m. CT. Read MoreJan 11, 2024
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Potential schizophrenia treatment, discovered at Vanderbilt and being developed by Neumora Therapeutics, entering Phase 1 clinical trial
In just over two years, a Vanderbilt-Neumora collaboration has led to the Phase 1 clinical trial of a treatment for schizophrenia spectrum disorders, which affect 3.7 million adults in the United States. This is the third chemical compound discovered at the Warren Center for Neuroscience Drug Discovery to reach Phase 1 clinical trials. Read MoreDec 4, 2023
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Warren Center for Neuroscience Drug Discovery added to Discovery Vanderbilt portfolio; philanthropic matching launched
Vanderbilt has announced the addition of the Warren Center for Neuroscience Drug Discovery into Discovery Vanderbilt as well as an initiative within the Dare to Grow campaign to inspire philanthropy with a one-to-one match for gifts of $100,000 or more. Read MoreDec 4, 2023
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Merryman, Lindsley make headway in drug development to cure pulmonary arterial hypertension
Research led by David Merryman, a professor of biomedical engineering, pharmacology and medicine who holds the Walters Family Chair, has resulted in the development of VU6047534, a new drug that treats pulmonary arterial hypertension—a type of high blood pressure that affects arteries in the lungs and in the heart—without serious neurological side effects. Merryman conducted... Read MoreSep 13, 2023
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Vanderbilt scientists make headway in drug development to cure pulmonary arterial hypertension
Biomedical engineer David Merryman and Warren Center for Neuroscience Drug Discovery director Craig Lindsley have developed a new drug that treats PAH, a type of high blood pressure that affects arteries in the lungs and in the heart, without serious neurological side effects. Read MoreSep 13, 2023
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Lindsley named 2022 fellow of American Society for Pharmacology and Experimental Therapeutics
Craig W. Lindsley, University Distinguished Professor of Pharmacology, Biochemistry and Chemistry, who holds the William K. Warren, Jr. Chair in Medicine, was recently announced as a 2022 fellow of the American Society for Pharmacology and Experimental Therapeutics for his demonstrated excellence and contributions to pharmacology and to the ASPET organization. Read MoreNov 29, 2022
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Vanderbilt, international collaborators discover treatment to slow neurodegenerative diseases
Warren Center for Neuroscience Drug Discovery lead researchers discover a therapy that may treat memory loss and slow the progression of Alzheimer’s disease. Read MoreNov 15, 2022
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Prothena and Warren Center for Neuroscience Drug Discovery collaborate on new Alzheimer’s disease therapeutics
Prothena and the Warren Center for Neuroscience Drug Discovery have entered into a collaborative research agreement to develop new small molecule therapeutics for the treatment of Alzheimer’s disease in individuals with Down syndrome. Read MoreApr 22, 2022
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Vanderbilt inks collaboration with precision neuroscience company Neumora to continue development of investigational treatment for neuropsychiatric disorders
Vanderbilt University has signed an exclusive worldwide license and research collaboration agreement with Neumora Therapeutics, Inc., a clinical-stage biotechnology company pioneering precision medicines for brain diseases through the integration of data science and neuroscience. Read MoreFeb 22, 2022
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Vanderbilt extends its longest ongoing drug discovery agreement with pharmaceutical company through 2023
Vanderbilt has extended its longest ongoing drug discovery agreement with Osaka, Japan-based Ono Pharmaceutical Co., Ltd., a research and development-oriented pharmaceutical company that is committed to creating innovative medicines in specific areas, through November 2023. Read MoreDec 21, 2021
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A potential new approach for the treatment of schizophrenia
Researchers discover how a protein may treat schizophrenia, including reversing working memory deficits, a hallmark of schizophrenia for which there is currently no treatment. Read MoreDec 8, 2021
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Vanderbilt-discovered drug candidate for Parkinson’s disease enters clinical trials
Appello Pharmaceuticals Inc. begins trial of a drug candidate that improves relief from symptoms of Parkinson’s disease without debilitating side effects. Read MoreOct 6, 2021
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Craig Lindsley named to Medicinal Chemistry Division of the American Chemical Society Hall of Fame
Craig Lindsley, the William K. Warren, Jr. Chair in Medicine and director of Vanderbilt’s Warren Center for Neuroscience Drug Discovery, will be inducted to the 2021 class of the Division of Medicinal Chemistry Hall of Fame. Read MoreJun 15, 2021
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Vanderbilt-developed obesity treatments will be advanced through collaboration with Soleno Therapeutics
A new partnership between Vanderbilt University’s Warren Center for Neuroscience Drug Discovery and clinical stage biopharmaceutical company Soleno Therapeutics will further research into new clinical treatments for multiple obesity syndromes. Read MoreFeb 25, 2021
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Discovery shows how to treat heart attacks; drug development underway
David Merryman has discovered that targeting a protein receptor in heart cells may limit a heart attack’s acute and long-term effects. Read MoreFeb 11, 2021
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American Chemical Society appoints Craig Lindsley editor in chief of ‘Journal of Medicinal Chemistry’
Craig Lindsley, William K. Warren, Jr. Chair in Medicine and university professor of chemistry, pharmacology and biochemistry, has been named editor in chief of the "Journal of Medicinal Chemistry." His appointment will begin Jan. 1. Read MoreDec 14, 2020
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Warren Center for Neuroscience Drug Discovery names Craig Lindsley as director
Craig Lindsley, the William K. Warren, Jr. Chair and University Professor of Pharmacology, Biochemistry and Chemistry, will become director of Vanderbilt University’s Warren Center for Neuroscience Drug Discovery, effective Dec. 1, 2020. Read MoreOct 20, 2020
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Committed to Memory: VU319 may hold the key to improving memory loss in Alzheimer’s patients
VU319, an investigational drug product developed by Vanderbilt researchers, targets one of medicine’s most bedeviling challenges: improving memory loss in people with Alzheimer’s disease. Read MoreJul 23, 2020