Aliquots
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How to fake a medical record
Simulated electronic health records could avoid patient privacy risks and help speed discovery. Read MoreNov 4, 2019
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Acute kidney injury recovery time impacts future risk
Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients. Read MoreOct 31, 2019
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Imaging host-pathogen battle for metal
An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies. Read MoreOct 31, 2019
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Another way to detect lymphedema
Early detection of lymphedema, which occurs in 20% of patients following breast cancer treatment, may improve therapeutic options for patients. Read MoreOct 22, 2019
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Completing DNA synthesis
James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis. Read MoreOct 21, 2019
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Microscopic spines connect worm neurons
Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology. Read MoreOct 17, 2019
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Less inflammation = better healing
Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes. Read MoreOct 17, 2019
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A new regulator of B cell development
New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells. Read MoreOct 8, 2019
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AI maps routes to heart disease
Machine learning on unlabeled electronic health record data has shed light on the emergence of cardiovascular disease. Read MoreOct 7, 2019
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A step toward gastric cancer
New research findings provide insight into the detrimental events that develop in response to H. pylori infection. Read MoreOct 3, 2019
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A catalog of DNA replication proteins
Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA. Read MoreOct 3, 2019
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Treating C. diff: new purpose for an old drug?
An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice. Read MoreSep 24, 2019
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Tailoring treatment for heart defect
By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants. Read MoreSep 23, 2019
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Microvilli in motion
Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border. Read MoreSep 19, 2019
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Potential prostate cancer biomarkers
An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk. Read MoreSep 19, 2019
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Relational memory in early psychosis
Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis. Read MoreSep 10, 2019
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Astrocytes and epilepsy
A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report. Read MoreSep 9, 2019
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How salt increases blood pressure
Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension. Read MoreSep 5, 2019
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The plus and minus of microtubules
Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer. Read MoreSep 5, 2019
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A “rheostat” for cancer signals
Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells. Read MoreAug 27, 2019