Aliquots

Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes. Read More

New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells. Read More

Machine learning on unlabeled electronic health record data has shed light on the emergence of cardiovascular disease. Read More

New research findings provide insight into the detrimental events that develop in response to H. pylori infection. Read More

Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA. Read More

An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice. Read More

By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants. Read More

Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border. Read More

An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk. Read More

Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis. Read More

A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report. Read More

Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension. Read More

Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer. Read More

Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells. Read More

Gene variants associated with cancer risk appear to contribute to carcinogenesis by regulating target genes that in turn promote the generation of mutations. Read More

Vanderbilt’s Bruce Carter and colleagues have discovered how genetic changes in the protein PMP22 may contribute to a disease of peripheral nerves. Read More

Combining immunotherapy and radiation therapy may be a powerful treatment approach for castration-resistant prostate cancer. Read More

Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health. Read More

Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer. Read More

Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases. Read More