Health And Medicine
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Phase 3 CELLEBRATE Trial testing regenerative stem cell-based therapy to improve urinary control for women
The Phase 3 CELLEBRATE trial to test a regenerative stem cell-based therapy in treating patients with stress urinary incontinence is continuing to recruit additional subjects after changing its study protocol to include only patients who have already tried surgery. Read MoreMar 11, 2024
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CLASS OF 2024: Hope through heartbreak fuels Vanessa Morales’ mission to help expecting mothers
WATCH: Hear how Bass Military Scholar Vanessa Morales is harnessing her personal experiences to make her a more compassionate nurse midwife. Read MoreMar 8, 2024
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Blood mutations increase risk for acute kidney injury: study
A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury, which occurs in more than 1 in 5 hospitalized adults worldwide. Read MoreMar 7, 2024
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CLASS OF 2024: Schyler Rowland finds a home in the lab, collaborating to fight diseases
WATCH: Learn how biomedical engineering major Schyler Rowland says mentors have inspired her future in fighting diseases Read MoreMar 1, 2024
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Rethinking drug efficacy: research aims to improve drug development
ASPIRE to Innovate Postdoctoral Fellow Catherine Leasure is the co-author of a comment article published this month in Nature Reviews Bioengineering addressing the pressing obstacle faced by modern drug development: worryingly poor success rates of pharmaceuticals progressing to clinical phases. Read MoreMar 1, 2024
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Vanderbilt biochemists discover breakthrough evolution-resistant compound to combat antibiotic resistance
Vanderbilt scientist Houra Merrikh led a team of researchers who discovered the first evolution-resistant chemical compound that prevents drug resistance development in bacteria. The compound is also a drug development platform that targets antimicrobial resistance during treatment of infections with antibiotics and evolution in general, Merrikh said. Read MoreMar 1, 2024
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Lippmann wins prestigious Chan Zuckerberg Initiative award to back research in the fight against Alzheimer’s
Ethan Lippmann, associate professor of chemical and biomolecular engineering and biomedical engineering, has won a Collaborative Pairs Pilot Project Award from the Chan Zuckerberg Initiative (CZI) to create a more effective way for the immune system to fight against neurodegenerative diseases like Alzheimer’s. Read MoreFeb 28, 2024
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Guengerich proposes paradigm shift in enzyme biochemistry
The lab of Professor of Biochemistry Fred Guengerich has proposed a paradigm shift in the understanding of a critical chemical reaction involved in sterol biosynthesis. Read MoreFeb 27, 2024
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Vanderbilt biochemists discover breakthrough anti-evolution compound to combat antibiotic resistance
The World Health Organization ranks antimicrobial resistance as one of the top ten global health risks. Vanderbilt researchers led by Houra Merrikh identified the first anti-evolution compound that targets AMR during treatment of infections with antibiotics. Read MoreFeb 26, 2024
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Exploring the basics of neurological disorders: Calcium transport in receptors
Led by Terunaga Nakagawa, an international collaboration describes for the first time the fundamental mechanism underpinning cellular processes that lead to learning and memory. Read MoreFeb 26, 2024
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Large, diverse genetic study of glaucoma implicates vascular and cancer-related genes
An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma, the most common type of glaucoma and the leading cause of irreversible blindness globally. Read MoreFeb 21, 2024
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VUMC part of major step to achieving precision medicine
An analysis of genomic data from nearly 250,000 participants in the National Institutes of Health’s All of Us Research Program has identified more than 275 million previously unreported genetic variations, nearly 4 million of which have potential health consequences. Read MoreFeb 19, 2024
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CLASS OF 2024: Discovery and communication key to biochemistry Ph.D. Kaitlyn Browning
WATCH: See how Ph.D. candidate Kaitlyn Browning wants to fight miscommunication and misinformation around science. Read MoreFeb 16, 2024
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Vanderbilt nanodrug may be a paradigm shift for cancer
A multidisciplinary research team at Vanderbilt University and Vanderbilt University Medical Center has discovered a new way to kill a tumor by disrupting its acidic “microenvironment” without harming normal tissue. Read MoreFeb 7, 2024
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VUMC study finds molecular switch key to repair of kidney damage
Researchers at Vanderbilt University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair. Read MoreFeb 7, 2024
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Watch Now: Lab-to-Table Conversation: ‘Picturing Progress: Representation in Scientific Art’
Join the next Lab-to-Table conversation, “Picturing Progress: Representation in Scientific Art” on Feb. 20 at 11:00 a.m. Read MoreFeb 7, 2024
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Combining unique methods, Kuriyan lab discovers new protein functions; explores physical space of proteins
Combining deep mutagenesis and cryo-EM reveals new conformational state of a protein responsible for high-speed DNA replication. The research builds on growing theories of molecular evolution. Read MoreFeb 6, 2024
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Fatty acids rewire energy supply chain in stomach cancer development
A study by Vanderbilt researchers has revealed how metabolic changes spurred by fatty acids contribute to the transformation of cells into abnormal versions of themselves that are the precursors to stomach cancer. Read MoreJan 31, 2024
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3D brain mapping opens a window to the aging brain
By mapping brain activity in three dimensions, researchers at Vanderbilt University Medical Center have achieved a more detailed picture of how the brain changes with age. Read MoreJan 30, 2024
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OpenFold authority Mohammed AlQuraishi, Columbia University, to deliver Apex Lecture on January 29
Mohammed AlQuraishi, assistant professor at Columbia University, will give an Apex Lecture on Monday, Jan. 29, at 12:00 p.m. CT in 214 Light Hall. His talk, “The State of Protein Structure Prediction and Friends,” is hosted by the School of Medicine Basic Sciences and co-sponsored by the Center for Applied AI in Protein Dynamics. Read MoreJan 22, 2024