Research
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Enzyme helps build motor that drives neuron death
The process, discovered in the axons of neurons, is implicated in Alzheimer’s, amyotrophic lateral sclerosis, traumatic brain injury and other diseases or injuries to the nervous system. Read MoreAug 6, 2018
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Expert: Inspiration, anger motivate women to run for office
Amanda Clayton can provide insight into why so many women are running for office in 2018--and how they might change Washington if they are elected. Read MoreAug 2, 2018
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Store brand spillover can dampen profits for national brands and retailers alike
Vanderbilt researchers examine what happens when store brands in one category of goods, like soup, creates demands in another category, like canned vegetables. Read MoreAug 2, 2018
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‘You don’t blow your diet on Twinkies’: Why consumers seek to maximize goal violations
When consumers contemplate violating a personal goal (i.e., cheating on a diet, overspending on a budget), they often seek to make the most of that violation by choosing the most extreme option, according to new research from Kelly Goldsmith. Read MoreAug 2, 2018
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Vanderbilt study links gene expression, disease association data
An international team of researchers led by Eric Gamazon has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases. Read MoreJul 27, 2018
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Understanding deaths from post-surgical complications
Robert Freundlich and colleagues analyzed records for nearly 1.2 million patients and found that, among patients who died within 30 days of surgery, one in five had a complication independently associated with mortality. Read MoreJul 20, 2018
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Fueling the MATE transporter
In new research, Hassane Mchaourab and colleagues have uncovered new insights into drug resistance that could lead to the development of new anti-cancer and antibacterial drugs. Read MoreJul 20, 2018
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Novel insights on “leaky” gut
Disruption of the integrity of the intestinal lining or epithelium contributes to a “leaky” gut and is a common feature of patients with inflammatory bowel disease. Yash Choksi, Christopher Williams and colleagues found that low levels of a certain protein exacerbated the condition. Read MoreJul 20, 2018
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Safe solid-state lithium batteries herald ‘paradigm shift’ in energy storage
Kelsey Hatzell studied the performance of a promising electrolyte for solid-state lithium batteries under real-world conditions. Read MoreJul 19, 2018
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Study reveals opioid patients face multiple barriers to treatment
In areas of the country disproportionately affected by the opioid crisis, treatment programs are less likely to accept patients paying through insurance of any type or accept pregnant women, a new Vanderbilt study found. Read MoreJul 12, 2018
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Team explores diabetes drug’s ability to treat RSV infection
A drug used to treat diabetes, liraglutide, may point to new therapies for respiratory syncytial virus (RSV) bronchiolitis — inflammation and obstruction of the lungs’ small airways. Read MoreJul 12, 2018
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Legalizing same-sex marriage increased health care access for gay men: Vanderbilt study
One of the first studies to examine the health impacts of legal marriage for LGBT individuals has found gay men were more likely to receive routine medical care following marriage legalization. Read MoreJul 11, 2018
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Mom may pass bacteria to baby in utero: Study
New findings by Jörn-Hendrik Weitkamp and colleagues provide the first account of bacterial signatures in mammalian fetal intestinal tissue. The results suggest that bacterial DNA moves from the mother’s microbiome into the fetal intestine, which may be a critical stimulus for normal mucosal immune development. Read MoreJul 5, 2018
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SMAD4 clue to colon cancer
Chronic inflammation is a predisposing condition for colorectal cancer, the third leading cause of cancer-related deaths in the United States. Anna Means, Ph.D., and colleagues have now linked inflammation-driven carcinogenesis in the colon to loss of an important signaling protein called SMAD4. Read MoreJul 5, 2018
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Vanderbilt licenses compound to Nashville’s Appello to advance Parkinson’s therapies
Appello was established with major investment from New York-based Deerfield Management, which specializes in accelerating drug development projects at universities and other nonprofits. Read MoreJun 29, 2018
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New research explains why some molecules have irregular forms
There’s one bond that had scientists stumped: the one between some types of metals and carbon. Professor of Chemistry Timothy Hanusa set out to replicate this unique type of bond using modeling. Read MoreJun 29, 2018
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Scavengers “protect” HDL
Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read MoreJun 29, 2018
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New staph virulence factor
The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections. Read MoreJun 28, 2018
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Vanderbilt engineers develop capabilities for more secure blockchain applications
Vanderbilt engineers have successfully developed and validated the feasibility of blockchain-based technologies for secure, confidential sharing of patient medical records in a case study that demonstrates how blockchain could solve a huge healthcare challenge. Read MoreJun 25, 2018
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Faster, more precise lab-on-a-chip holds promise of early cancer diagnosis
Justus Ndukaife, who won the 2017 Chorafas Foundation Prize in Physics for his nanotweezers work, also recently was selected for the Carnegie African Diaspora Fellowship Program. Read MoreJun 25, 2018