Research

New research from Sandra Rosenthal, Jack and Pamela Egan Professor of Chemistry and professor of pharmacology and chemical and biomolecular engineering, suggests that the rate of change in solar insolation—that is, the amount of solar radiation that reaches the ground over a specified time in a given location—has a greater impact on these depressive disorders than routine seasonal changes in sunlight. Read More

Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity. Read More

Vanderbilt researchers Sokrates Pantelides and Joshua Caldwell are part of an international collaboration that has demonstrated a new way to manipulate and measure subtle atomic vibrations in nanomaterials. This breakthrough could make it possible to develop customized functionalities to improve on and build new technologies. Sokrates Pantelides (Vanderbilt University) Joshua Caldwell (Vanderbilt University) Electron beams... Read More

A new study found that several, but not all, of the human monoclonal antibodies used clinically to prevent patients from becoming severely ill from COVID-19 may not be protective against the Omicron variant now sweeping across the United States. Read More

A new data portal called Cancer-Immu established by a team of Vanderbilt University Medical Center biostatisticians can help cancer clinicians and researchers predict which patients will respond to immune checkpoint inhibitors. Read More

A severe burn injury is not static. Within 72 hours, partial thickness burns can progress, or convert, to full thickness burns, greatly increasing the risk of infection, incapacitating scarring, and even death. Preventing the conversion is one of the most challenging aspects of treating burns, and a trans-institutional team of researchers from Vanderbilt University Medical... Read More

Janos Salloi. PhD’08, is company’s chief technology officer Gunshot detection technology developed by Vanderbilt engineers and commercialized by a longtime research partner recently helped lead to an arrest in a fatal shooting in Las Vegas. Within seconds of the first shot in late August 2021, 16 sensors located along the Freemont Street Experience pedestrian mall... Read More

New research finds that fully vaccinated patients with cancer who had breakthrough COVID-19 infections remained at high risk for hospitalization and death. Read More

There is strong evidence that the medication apixaban (Eliquis) is preferable to rivaroxaban (Xarelto) for stoke prevention in patients with atrial fibrillation (AF), with both reduced rates of severe bleeding complications as well as strokes, according to study published Dec. 21 in JAMA. Read More

Researchers at Vanderbilt University Medical Center have constructed a single-cell “atlas” of lung development that tracks multiple cell types over time. Read More

by Paul Govern Information based biomedical discovery, in particular the push toward precision medicine, depends on open-ended analysis of de-identified data from patients and research participants on the largest possible scale. Sharing data while controlling the risk of data reidentification under privacy attack is vital to the enterprise. Zhiyu Wan Game theory indicates that only... Read More

Two devices for placing a breathing tube during critical illness had similar success rates for intubation on the first attempt, according to a study published Dec. 8 in JAMA. Read More

Vanderbilt researchers identified a critical role for IL-1beta signaling in leukemia cells with a certain mutation, suggesting this pathway may be a good target for novel treatments. Read More

Vanderbilt researchers suggest that to reduce treatment-related regret for men with localized prostate cancer, treatment preparation should focus on shared decision-making and aligning patient expectations with treatment toxicity. Read More

In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11 with moderate-to-severe asthma, offering a new option to these patients. Read More

New research shows the potential to identify therapeutic directions that could improve outcomes for people who stutter. Read More

In a review of 100 years of research on the sensory systems in whales, Rachel Racicot, research assistant professor of biological sciences, describes advances in the field and key questions that remain. Read More

Researchers in the Endocrine Neoplasia Research Laboratory at Vanderbilt University Medical Center have received national recognition for their work to discover better treatments for thyroid cancer. A paper describing their lab work was awarded first place in the Basic Science category at the 2021 Cancer Research Competition. Read More

Researchers across four health care systems, including Vanderbilt University Medical Center, have found that increased depression polygenic scores are associated with increased white blood cell count, highlighting the importance of the immune system in the etiology of depression. Read More

Kolouri wins $1M DARPA grant to investigate AI cooperative lifelong learning A Vanderbilt engineering professor is leading part of an international initiative to create advanced artificial intelligence programs that will enable machines to learn progressively over a lifetime and share those experiences with each other. Researchers hope the technology will allow machines to reuse information,... Read More