Research

Vanderbilt team to focus on engineering, testing the device by Matt Batcheldor Vanderbilt University Medical Center will share in an $8.7 million federal grant to create an artificial lung system that patients with incurable lung disease can use at home. The Department of Defense Congressionally Directed Medical Research Program (CDMRP) grant will fund research to create... Read More

Red blood cell distribution width has prognostic value for many diseases, but it was not associated with overall survival in patients with glioblastoma, Vanderbilt researchers found. Read More

Ege Kavalali and Heidi Hamm collaborated to discover a signaling pathway for how spontaneous release of neurotransmitters can be selectively regulated without disrupting evoked action potentials. Read More

A common Type 2 diabetes treatment being tested for hypothalamic obesity had unexpected results on weight loss and total energy expenditure, Vanderbilt researchers report. Read More

Surgical removal of the colon for recurrent diverticulosis varies by geographic region and is associated with surgeon and hospital factors; stronger national guidelines are needed, Vanderbilt researchers report. Read More

Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, possibly explaining some health disparities associated with COVID-19. Read More

Vanderbilt research has revealed an important mechanism in the kidney by which a cell surface receptor known as DDR1 fans the flames of inflammation and fibrosis that ultimately lead to kidney failure. Read More

Vanderbilt researchers test and recommend statistical approaches to study the association between engagement with digital health interventions and clinical outcomes. Read More

New research from Sandra Rosenthal, Jack and Pamela Egan Professor of Chemistry and professor of pharmacology and chemical and biomolecular engineering, suggests that the rate of change in solar insolation—that is, the amount of solar radiation that reaches the ground over a specified time in a given location—has a greater impact on these depressive disorders than routine seasonal changes in sunlight. Read More

Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity. Read More

Vanderbilt researchers Sokrates Pantelides and Joshua Caldwell are part of an international collaboration that has demonstrated a new way to manipulate and measure subtle atomic vibrations in nanomaterials. This breakthrough could make it possible to develop customized functionalities to improve on and build new technologies. Sokrates Pantelides (Vanderbilt University) Joshua Caldwell (Vanderbilt University) Electron beams... Read More

A new study found that several, but not all, of the human monoclonal antibodies used clinically to prevent patients from becoming severely ill from COVID-19 may not be protective against the Omicron variant now sweeping across the United States. Read More

A new data portal called Cancer-Immu established by a team of Vanderbilt University Medical Center biostatisticians can help cancer clinicians and researchers predict which patients will respond to immune checkpoint inhibitors. Read More

A severe burn injury is not static. Within 72 hours, partial thickness burns can progress, or convert, to full thickness burns, greatly increasing the risk of infection, incapacitating scarring, and even death. Preventing the conversion is one of the most challenging aspects of treating burns, and a trans-institutional team of researchers from Vanderbilt University Medical... Read More

Janos Salloi. PhD’08, is company’s chief technology officer Gunshot detection technology developed by Vanderbilt engineers and commercialized by a longtime research partner recently helped lead to an arrest in a fatal shooting in Las Vegas. Within seconds of the first shot in late August 2021, 16 sensors located along the Freemont Street Experience pedestrian mall... Read More

New research finds that fully vaccinated patients with cancer who had breakthrough COVID-19 infections remained at high risk for hospitalization and death. Read More

There is strong evidence that the medication apixaban (Eliquis) is preferable to rivaroxaban (Xarelto) for stoke prevention in patients with atrial fibrillation (AF), with both reduced rates of severe bleeding complications as well as strokes, according to study published Dec. 21 in JAMA. Read More

Researchers at Vanderbilt University Medical Center have constructed a single-cell “atlas” of lung development that tracks multiple cell types over time. Read More

by Paul Govern Information based biomedical discovery, in particular the push toward precision medicine, depends on open-ended analysis of de-identified data from patients and research participants on the largest possible scale. Sharing data while controlling the risk of data reidentification under privacy attack is vital to the enterprise. Zhiyu Wan Game theory indicates that only... Read More

Two devices for placing a breathing tube during critical illness had similar success rates for intubation on the first attempt, according to a study published Dec. 8 in JAMA. Read More