Research

Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies. Read More

A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque in blood vessels in mice potentially could lead to a new approach for treating atherosclerosis in humans, according to researchers at Vanderbilt University Medical Center. Read More

Researchers at Vanderbilt University Medical Center have identified antibodies that, in animals, block infection by alphaviruses, which can cause chronic and debilitating joint pain and arthritis and are an increasing global health concern. Read More

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reported Aug. 17 in the Proceedings of the National Academy of Sciences. Read More

Developing atomically thin graphene membranes used to separate salt from water is extraordinarily complex and the effort grows more crucial as population growth, industrialization and climate change strain freshwater resources. Vanderbilt engineering researchers report a breakthrough in scalable fabrication of graphene membrane with a sealing technology that corrects variations in the pore size so they... Read More

Mark Does, professor of biomedical engineering has been selected as a Fellow of the International Society for Magnetic Resonance in Medicine. His research program focuses on developing and applying MRI methods to quantitatively characterize various properties and/or compositions of tissue. It includes developing models of nuclear magnetic resonance relaxation and water diffusion in tissue, development... Read More

An inflammatory factor in mucus could be a biomarker of treatment-resistant chronic sinusitis used to determine which patients are at risk for repeat sinus surgery. Read More

Craig Duvall, Cornelius Vanderbilt Professor of Engineering, has been elevated to the rank of Fellow of the Biomedical Engineering Society. Duvall and his research program focus on development of technologies for controlled drug release, tissue regeneration and therapeutics, and delivery of intracellular-acting biologic drugs such as siRNA and peptide therapeutics. The applications of these technologies... Read More

Each week a woman consumes alcohol during the first five to 10 weeks of pregnancy is associated with an incremental 8% increase in risk of miscarriage, according to a study published this week by Vanderbilt University Medical Center researchers. Read More

A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention. Read More

Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines. Read More

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer. Read More

Appendiceal cancer — cancer of the appendix — is a rare malignancy that is usually found during surgery for acute appendicitis. Although the rate of appendectomies has been stable over the last two decades, the incidence of malignant appendiceal cancer increased 232% in the United States. Read More

Non-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic white Americans. A new study breaks down this risk according to specific ethnicities and locations within the stomach. Read More

A team of Vanderbilt University and Vanderbilt University Medical Center researchers has received a $3.1 million National Institutes of Health (NIH) grant to develop advanced, patient-specific cochlear implant stimulation models for customized implant programming. Read More

Researchers from Vanderbilt University and Vanderbilt University Medical Center have received a $1.4 million grant from the National Eye Institute at the National Institute of Health to identify surgical techniques that improve vision after macular hole repair. Read More

The multicellular, 3-D structure of human pancreatic islets — the areas of the pancreas containing hormone-producing or endocrine cells — has presented challenges to researchers as they study and manipulate these cells’ function, but Vanderbilt University Medical Center researchers have now developed a pseudoislet system that allows for much easier study of islet function. Read More

A protein linked to amyotrophic lateral sclerosis (ALS), a progressive neurological disease that causes muscle weakness, may be a key to treating fibrotic disease of the kidneys and other organs, researchers at Vanderbilt University Medical Center reported recently. Read More

Vanderbilt researchers conducted the largest analysis to date of a heart complication in children following stem cell transplant. The findings may help guide screening practices to improve outcomes. Read More

Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered. Read More