Research

Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients. Read More

Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction. Read More

Vanderbilt University Medical Center has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of “convalescent plasma” as a treatment for COVID-19. Read More

Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption. Read More

All software is not created equal. At one end are apps on a smartphone and consumer-facing programs for which periodic updates to fix bugs and security issues are routine, like replacing an air conditioning filter or getting an annual flu shot. At the other end are large, complex software systems such as software used in... Read More

Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies. Read More

A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque in blood vessels in mice potentially could lead to a new approach for treating atherosclerosis in humans, according to researchers at Vanderbilt University Medical Center. Read More

Researchers at Vanderbilt University Medical Center have identified antibodies that, in animals, block infection by alphaviruses, which can cause chronic and debilitating joint pain and arthritis and are an increasing global health concern. Read More

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reported Aug. 17 in the Proceedings of the National Academy of Sciences. Read More

Developing atomically thin graphene membranes used to separate salt from water is extraordinarily complex and the effort grows more crucial as population growth, industrialization and climate change strain freshwater resources. Vanderbilt engineering researchers report a breakthrough in scalable fabrication of graphene membrane with a sealing technology that corrects variations in the pore size so they... Read More

Mark Does, professor of biomedical engineering has been selected as a Fellow of the International Society for Magnetic Resonance in Medicine. His research program focuses on developing and applying MRI methods to quantitatively characterize various properties and/or compositions of tissue. It includes developing models of nuclear magnetic resonance relaxation and water diffusion in tissue, development... Read More

An inflammatory factor in mucus could be a biomarker of treatment-resistant chronic sinusitis used to determine which patients are at risk for repeat sinus surgery. Read More

Craig Duvall, Cornelius Vanderbilt Professor of Engineering, has been elevated to the rank of Fellow of the Biomedical Engineering Society. Duvall and his research program focus on development of technologies for controlled drug release, tissue regeneration and therapeutics, and delivery of intracellular-acting biologic drugs such as siRNA and peptide therapeutics. The applications of these technologies... Read More

Each week a woman consumes alcohol during the first five to 10 weeks of pregnancy is associated with an incremental 8% increase in risk of miscarriage, according to a study published this week by Vanderbilt University Medical Center researchers. Read More

A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention. Read More

Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines. Read More

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer. Read More

Appendiceal cancer — cancer of the appendix — is a rare malignancy that is usually found during surgery for acute appendicitis. Although the rate of appendectomies has been stable over the last two decades, the incidence of malignant appendiceal cancer increased 232% in the United States. Read More

Non-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic white Americans. A new study breaks down this risk according to specific ethnicities and locations within the stomach. Read More

A team of Vanderbilt University and Vanderbilt University Medical Center researchers has received a $3.1 million National Institutes of Health (NIH) grant to develop advanced, patient-specific cochlear implant stimulation models for customized implant programming. Read More