Research

There is huge momentum toward adoption of battery electric vehicles primarily because performances are meeting or exceeding the properties of traditional automobiles. Consumers want electric vehicles that have similar driving range (energy density) and charging styles and times (power density) to gasoline powered vehicles. “One pathway to improving the energy density of the battery, or... Read More

A new method that keeps microbes and gut cells together will be useful for studies of complex host-microbe interactions and for analysis of clinical specimens. Read More

Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals. Read More

It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection. Read More

Researchers at Vanderbilt University Medical Center have identified a key factor that coordinates the body’s repair response to severe injury in the stomach caused, most commonly, by infection by the bacterium Helicobacter pylori. Read More

The brain’s response to low oxygen — growth and remodeling of blood vessels — involves certain cell types and molecular pathways, Vanderbilt researchers have discovered. Read More

Vanderbilt biomedical engineers receive NIH funding to continue the development of a rapid, precise, in-office test for respiratory infections including COVID-19. Read More

AstraZeneca is advancing into phase 3 clinical trials with an investigational COVID-19 therapy of two long-acting antibodies discovered by Vanderbilt University Medical Center and optimized by AstraZeneca. Read More

A computer-based method developed at Vanderbilt University Medical Center that scans electronic medical records (EMRs) for genetic contributors to disease has been used for the first time to reveal the impact of race on health. Read More

Researchers at Vanderbilt University Medical Center have generated the first comprehensive molecular “atlas” of genes expressed by the neuronal cells within the intestine that coordinate the functions of the gastrointestinal (GI) tract. Read More

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found. Read More

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication. Read More

For more than a decade Matt Lang and collaborators across the U.S. have worked to recreate key components of T-cells and how they know when to start fighting disease. Conventional wisdom suggested that T-cells formed regular, force-free bonds with infected cells, and in doing so caused the chain reaction of immune response. The team slowly... Read More

A new, $8.7 million project—Design. R–AI-assisted CPS Design—involves pathbreaking work for the Defense Advanced Research Projects Agency as future cyber-physical systems will rely less on human control and more machine learning algorithms and artificial intelligence processors. Read More

Vanderbilt researchers awarded one of NSF’s 24 new projects to drive future manufacturing One of the challenges of drug delivery systems is to optimize their targeting properties so therapeutic compounds used in smaller amounts reach only a specific area of the body and result in little or no side effects. The ability to engineer the... Read More

Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment. Read More

Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction. Read More

Cody Siciliano, PhD, assistant professor of Pharmacology in the Vanderbilt University School of Medicine, has been selected to receive a one-year, $100,000 research award from the Stanley Cohen Innovation Fund to support his studies of the neural substrates of memory. Read More

Vanderbilt researchers have been awarded a National Science Foundation Convergence Accelerator 2020 Cohort Phase 1 grant to create a standardized platform that will streamline the development, testing and dissemination of technology that can improve human health. The nine-month project, “Scalable, Traceable AI for Imaging Translation: Innovation to Implementation for Accelerated Impact (STRAIT I3),” looks specifically... Read More

NSF Convergence grant dovetails with Microsoft PREMONITION program expansion Vanderbilt engineers are leading the academic component of a massive Microsoft project that combines robotics, genomics, big data collection—and mosquitos—to monitor the environment and detect potential pandemics and other threats before they cause widespread outbreaks. Microsoft announced today expansion of its PREMONITION program and a large-scale... Read More