Research

A new study from Vanderbilt epidemiologists suggests that it’s time to reconsider clinical practice guidelines for the treatment of early-stage breast cancer in older women. Read More

Twenty-nine prominent faculty from across campus comprise Vanderbilt University’s latest endowed chair honorees. They include scholars working in diverse areas—from election analysis and lung cancer research to the nascent field of neurolaw, exploring the brain mechanism underlying legal decision-making. Read More

Perfecting MRI images with deep learning, Vanderbilt and VUMC researchers have created a technique that corrects image distortions, which provides more accurate information for researchers, radiologists and neuroscientists to better interpret brain scans. The work by Bennett Landman, professor of electrical engineering and computer science and radiology and radiological sciences, and Kurt Schilling, research assistant... Read More

A new study sheds light on how molecular subsets within the tumors of kidney cancer patients determine treatment outcomes and underscores the importance of personalized medicine in making therapy decisions. Read More

Findings from a national study published Nov. 9 in the Journal of the American Medical Association (JAMA) “do not support” the use of hydroxychloroquine for the treatment of adult patients hospitalized with COVID-19, the report concludes. Read More

Diabetes drugs known as GLP-1 receptor agonists, such as exenatide (Byetta), are a promising and safe treatment for a rare form of obesity. Read More

Vanderbilt University Medical Center has begun recruiting up to 250 participants for a Phase 3 clinical trial testing an investigational COVID-19 vaccine candidate developed by the Janssen Pharmaceutical Companies of Johnson & Johnson. Read More

Peptides derived from the antimicrobial peptides secreted by frogs could function as microbicides to limit HIV transmission, while sparing protective vaginal bacteria. Read More

Angelika Amon, PhD, a pioneering cell and molecular biologist and winner of the 2018 Vanderbilt Prize in Biomedical Science, died Oct. 29 from cancer. She was 53. Read More

An innovative Vanderbilt program that brings together scientists and artists with the shared goal of scientific communication is set to expand with support from a three-year grant from the Burroughs Wellcome Fund. Read More

Histamine — commonly associated with allergies — also has a signaling role in the brain’s reward center and may offer a novel target for treating addiction. Read More

Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo. Read More

A trans-institutional team of Vanderbilt engineering, data science and clinical researchers has developed a novel approach for monitoring bone stress in recreational and professional athletes, with the goal of anticipating and preventing injury. Using machine learning and biomechanical modeling techniques, the researchers built multisensory algorithms that combine data from lightweight, low-profile wearable sensors in shoes... Read More

Researchers at Vanderbilt University Medical Center played a key role in the development of remdesivir, the first drug approved by the U.S. Food and Drug Administration for the treatment of COVID-19. Read More

Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox. Their approach, described in the journal Nature Genetics, integrates vast genomics datasets to predict gene expression and facilitate discovery of genetic mechanisms underlying human diseases. Read More

There is huge momentum toward adoption of battery electric vehicles primarily because performances are meeting or exceeding the properties of traditional automobiles. Consumers want electric vehicles that have similar driving range (energy density) and charging styles and times (power density) to gasoline powered vehicles. “One pathway to improving the energy density of the battery, or... Read More

A new method that keeps microbes and gut cells together will be useful for studies of complex host-microbe interactions and for analysis of clinical specimens. Read More

Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals. Read More

It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection. Read More

Researchers at Vanderbilt University Medical Center have identified a key factor that coordinates the body’s repair response to severe injury in the stomach caused, most commonly, by infection by the bacterium Helicobacter pylori. Read More