Pathology Microbiology And Immunology

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine. Read More

Vanderbilt investigators report that dysregulation of certain immune cells in the intestines may lead to inflammation and disease. Read More

Infectious diseases specialist David Aronoff, M.D., recently became one of 73 new fellows of the American Academy of Microbiology, an honorific leadership group within the American Society of Microbiology. Read More

Pathologist Carol Rauch, M.D., Ph.D., likes being prepared. Read More

(photo by Anne Rayner) The Rockefeller University’s Paul Bieniasz, Ph.D., center, here with Vanderbilt’s Samuel Santoro, Ph.D., left, and Christopher Aiken, Ph.D., discussed his research on retroviruses at his recent Flexner Discovery Lecture, which was sponsored by the Department of Pathology, Microbiology and Immunology. Read More

James Crowe Jr., M.D., director of the Vanderbilt Vaccine Center, is the 2017 recipient of the Stanley J. Korsmeyer Award given by the American Society for Clinical Investigation (ASCI), one of the nation’s oldest and most respected honor societies for physician-scientists. Read More

Paul Bieniasz, Ph.D., a pioneer in the study of retroviruses, will deliver the next Flexner Discovery Lecture on Thursday, March 9. Read More

James Crowe Jr., M.D., director of the Vanderbilt Vaccine Center, is the 2017-2018 recipient of the Samuel Rosenthal Prize for Excellence in Academic Pediatrics. Read More

Scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart’s amazing biomechanical properties in order to study cardiac disease, develop heart drugs. Read More

The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection. Read More

High dose flu vaccine boosts the immune response in older adults by increasing activation of certain immune cells. Read More

The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response. Read More

Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. Read More

Vanderbilt investigators recommend that the presence of tumor deposits in the abdomen be included when staging midgut neuroendocrine tumors. Read More

A new method will make it possible to study solid tumors and healthy tissues using mass cytometry. Read More

A novel drug that targets the protein RSK blocked aggressive breast cancers from metastasizing in an animal model. Read More

Vanderbilt University Medical Center (VUMC) has established a Sarcoidosis Center of Excellence under the direction of Wonder Drake, M.D., associate professor of Medicine and Pathology, Microbiology and Immunology. Read More

Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered. Read More

At the intersection of immunology and metabolism is a burgeoning new field: immunometabolism. It’s an area where Vanderbilt has exceptional strengths, said Jeffrey Rathmell, Ph.D., Cornelius Vanderbilt Professor of Immunobiology. Read More

Researchers at Vanderbilt University Medical Center and Washington University School of Medicine in St. Louis have isolated a human monoclonal antibody that in a mouse model “markedly reduced” infection by the Zika virus. Read More