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pathology microbiology and immunology Archives

Versatile C. difficile blocker

Jan. 26, 2018—New research reveals a unique mechanism of C. difficile toxin neutralization by a monoclonal antibody, suggesting new therapeutic approaches.

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Lighting up iron levels

Jan. 11, 2018—A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease.

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Young named chief medical officer of American Red Cross

Jan. 4, 2018—Vanderbilt’s Pampee Young, MD, PhD, has been named chief medical officer of the American Red Cross.

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Asthma study may point to potential new therapeutic approach

Jan. 4, 2018—New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition.

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Crowe elected a fellow of the National Academy of Inventors

Dec. 14, 2017—James Crowe Jr., MD, director of the Vanderbilt Vaccine Center at Vanderbilt University Medical Center (VUMC), has been named a fellow of the National Academy of Inventors (NAI).

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Bioactive lipids and rheumatoid arthritis

Nov. 1, 2017—An enzyme that produces bioactive fatty acids has elevated activity in patients with rheumatoid arthritis, supporting further studies to understand its biologic roles in the disease.

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A switch for autoimmunity

Oct. 12, 2017—Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies.

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Excess dietary manganese increases risk of staph infection in heart

Sep. 21, 2017—Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”).

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Restricting HIV-1 infection

Sep. 1, 2017—Vanderbilt researchers are discovering ways that host proteins block HIV-1 infection, which could suggest new avenues for treatment.

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Investigators use light to kill microbial ‘vampires’

Jul. 27, 2017—On July 24 Vanderbilt scientist Eric Skaar, Ph.D., MPH, summarized his group’s latest paper in a tweet: “If S. aureus is going to drink our blood like a vampire, let's kill it with sunlight.”

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Probing the genetics of autoimmunity

Jul. 21, 2017—Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets.

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Immune responses linked to cell’s recycling system

Jul. 20, 2017—Autophagy is the cellular equivalent of trash pickup and recycling — it is a process by which proteins, protein aggregates and damaged cellular organelles are degraded in order to reuse nutrients and promote cellular metabolism.

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