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pathology microbiology and immunology

Cellular engines of wound repair have distinct roles

Aug. 8, 2019—Vanderbilt investigators have now discovered that, in contrast to prevailing dogma, fibroblasts are not all alike; instead, they have distinctive functions following tissue injury.

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Intestinal immune cell interactions

Jul. 30, 2019—Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.

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Vanderbilt team shows how stomach bug can trigger cancer

Jul. 11, 2019—Researchers at Vanderbilt University and the University of Michigan in Ann Arbor have obtained the first high-resolution image of a molecular “machine” used by the insidious stomach bug Helicobacter pylori (H. pylori) to inject a cancer-causing protein into the stomach lining.

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Vanderbilt vaccine pioneer James Crowe honored with major science prize

Jul. 9, 2019—James Crowe Jr., MD, director of the Vanderbilt Vaccine Center, will be honored today by the science and technology company Merck KGaA, Darmstadt, Germany for his contributions to developing new therapeutics and vaccines against some of the world’s deadliest viruses.

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New method tested to block chikungunya infection

Jun. 14, 2019—Scientists are testing a new way to fight chikungunya virus that involves injecting genetic material into the bodies of infected and at-risk individuals to trigger rapid production of potent, virus-neutralizing antibodies.

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VUMC joins international effort to speed vaccine development

Jun. 6, 2019—VUMC has joined an international effort to streamline and accelerate development of vaccines and other treatments against a growing worldwide surge of deadly and debilitating viral infections.

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Frog fungus fights back

May. 15, 2019—Louise Rollins-Smith and colleagues have discovered a new way that a deadly fungus evades frogs' immune systems.

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How bugs overcome host defenses

Apr. 12, 2019—Eric Skaar and colleagues have figured out how a common bug responsible for ventilator-associated pneumonia responds when starved of zinc, a metal it needs to survive, which may lead to new therapeutic targets for the dangerous infection.

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Research shows frogs can adapt to traffic noise

Feb. 21, 2019—Frogs don’t like living near noisy highways any better than people do, but research from Vanderbilt suggests that frogs, like hardened city-dwellers, can learn to adapt to the constant din of rumbling trucks, rolling tires and honking horns.

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Probing H. pylori cancer protein

Feb. 15, 2019—Timothy Cover, john Loh and colleagues have identified how a certain type of mutation influences the risk of premalignant and malignant changes in the stomach.

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Destructive ‘telegrams’ in asthma

Jan. 31, 2019—Heather Pua and colleagues have identified the source of cellular signals that may play a role in triggering an asthma attack.

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VUMC scientists ‘sprint’ to find anti-Zika antibodies

Jan. 25, 2019—Scientists at Vanderbilt University Medical Center and colleagues in Boston, Seattle and St. Louis are racing to develop — in a mere 90 days — a protective antibody-based treatment that can stop the spread of the Zika virus.

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