Pathology Microbiology And Immunology
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Team isolates antibodies that neutralize GI bug norovirus
The discovery of these antibodies could significantly improve the diagnosis and treatment of the leading cause of stomach illness in the world. Read MoreAug 30, 2018
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Team finds potent antibodies against three Ebola viruses
Researchers led by James Crowe Jr. are a step closer to developing a broadly effective antibody treatment against the three major Ebola viruses that cause lethal disease in humans. The hope is that the antibodies — like heat-seeking missiles — would seek out and destroy the viruses before they can wreak havoc in the body. Read MoreJul 19, 2018
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New staph virulence factor
The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections. Read MoreJun 28, 2018
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Karijolich named 2018 Pew Biomedical Scholar
John Karijolich, PhD, assistant professor of Pathology, Microbiology, and Immunology at Vanderbilt University Medical Center, has been named a Pew Biomedical Scholar by The Pew Charitable Trusts. Read MoreJun 14, 2018
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A “public” target for HIV
Common sequences of antibodies against HIV may be key to developing a successful vaccine strategy for the virus. Read MoreJun 8, 2018
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New target to stop Ebola
A new Vanderbilt study suggests it may be possible to develop antibody therapies or a universal vaccine effective against multiple Ebola virus family members. Read MoreMay 21, 2018
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Alphavirus “Achilles heel”
Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses. Read MoreMay 17, 2018
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Study finds acetaminophen helps reduce acute kidney injury risk in children following cardiac surgery
Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics. Read MoreMay 14, 2018
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Putting the brakes on sepsis
An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection. Read MoreMay 9, 2018
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Ware elected VP of clinical investigation society
With last week’s election of Lorraine Ware, MD, as vice president of the American Society for Clinical Investigation (ASCI), two faculty members of the Vanderbilt University School of Medicine are among the current officers of the elite physician-scientist honor society. Read MoreApr 26, 2018
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Disease-fighting antibody production
New research links nutrient-responsive cellular signaling to the antibody-mediated immune response. Read MoreApr 20, 2018
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New labeling system speeds clinical lab turnaround times
Much of everyday clinical decision-making is informed by lab tests performed rapidly on automated instrumentation — basic metabolic panels, complete blood counts, all the lab orders for which clinicians expect quick results. Read MoreApr 19, 2018
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Study reveals frogs bouncing back in Panama
A new study reports that some Central American frog species are recovering from a deadly fungal epidemic, perhaps because they have better defenses against the pathogen. Read MoreApr 5, 2018
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New imaging approach offers unprecedented views of staph infection
A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state. Read MoreMar 15, 2018
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Hope for an RSV vaccine
Newly discovered features in an RSV protein may be useful for rational structure-based vaccine design. Read MoreFeb 23, 2018
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Versatile C. difficile blocker
New research reveals a unique mechanism of C. difficile toxin neutralization by a monoclonal antibody, suggesting new therapeutic approaches. Read MoreJan 26, 2018
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Lighting up iron levels
A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease. Read MoreJan 11, 2018
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Young named chief medical officer of American Red Cross
Vanderbilt’s Pampee Young, MD, PhD, has been named chief medical officer of the American Red Cross. Read MoreJan 4, 2018
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Asthma study may point to potential new therapeutic approach
New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition. Read MoreJan 4, 2018
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Crowe elected a fellow of the National Academy of Inventors
James Crowe Jr., MD, director of the Vanderbilt Vaccine Center at Vanderbilt University Medical Center (VUMC), has been named a fellow of the National Academy of Inventors (NAI). Read MoreDec 14, 2017