NIH

Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals. Read More

Biologists reveal that tissue perturbations by chemotherapy agents promote stem cell expansion and that fibroblast cells exhibit unexpected, immune-like behavior. Read More

It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection. Read More

Vanderbilt biomedical engineers receive NIH funding to continue the development of a rapid, precise, in-office test for respiratory infections including COVID-19. Read More

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found. Read More

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication. Read More

For more than a decade Matt Lang and collaborators across the U.S. have worked to recreate key components of T-cells and how they know when to start fighting disease. Conventional wisdom suggested that T-cells formed regular, force-free bonds with infected cells, and in doing so caused the chain reaction of immune response. The team slowly... Read More

Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment. Read More

Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction. Read More

Understanding immunity generated by smallpox vaccine may hold lessons for COVID-19 vaccine development. Read More

Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics. Read More

An international group of researchers including Vanderbilt epidemiologists has identified new DNA methylation biomarkers associated with prostate cancer risk. Read More

Eric Gamazon, PhD, assistant professor of Medicine, has been awarded a $1.5 million grant from the National Human Genome Research Institute, part of the National Institutes of Health (NIH), to develop novel computational tools that integrate functional genomic data and electronic health records. Read More

Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance. Read More

Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease. Read More

Tina Iverson and colleagues provide a structural view into the assembly of a protein machine essential for cellular energy production. Read More

Vanderbilt engineers have received a $1.4 million NIH grant to work toward a compact, silent, less expensive and potentially portable MRI device. Read More

Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients. Read More

Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction. Read More

Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption. Read More