NIH

New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines. Read More

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health. Read More

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy. Read More

A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage. Read More

An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain. Read More

The Office of the Provost, as part of the Provost's Initiative to Enhance Research and Scholarship (PIERS), is providing a campuswide educational workshop Oct. 9 to support the diversification of faculty research portfolios. Read More

Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer. Read More

Vanderbilt (VU and VUMC, collaboratively) is anticipating the opportunity to nominate one candidate for the Brain Research Foundation Fay/Frank Seed Grant Program for 2018. Read More

Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation. Read More

Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked. Read More

Vanderbilt researchers are discovering ways that host proteins block HIV-1 infection, which could suggest new avenues for treatment. Read More

Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease. Read More

New insights into the long-lasting effects of Fragile X syndrome on connections in the brain during early development highlight the importance of early detection and treatment. Read More

Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders. Read More

Assessing brain functional and structural connectivity in patients with temporal lobe epilepsy may be a useful way to identify the best candidates for surgical treatment. Read More

Based on findings from Vanderbilt investigators and others, clinical trials of estrogen inhibition for pulmonary arterial hypertension have recently been approved and funded by the National Institutes of Health. Read More

It takes a minuscule amount of force to make T cells behave in the lab as they behave in the body. That finding is a leap in cancer therapy research. Read More

New findings could explain the link between chronic stress and reduced survival in women diagnosed with breast cancer, and could lead to new strategies to improve treatment outcomes. Read More

Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers. Read More

Although drug addiction is classically studied in a neuron-centric way, Vanderbilt researchers have discovered that the immune system also plays a critical role. Read More