NIH
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Scavengers “protect” HDL
Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read MoreJun 29, 2018
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New staph virulence factor
The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections. Read MoreJun 28, 2018
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Novel infection fighter
A drug in use clinically to help make vaccines more effective may be a powerful new tool for fighting antibiotic-resistant infections. Read MoreJun 13, 2018
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Confronting TB resistance
Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis. Read MoreJun 11, 2018
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A “public” target for HIV
Common sequences of antibodies against HIV may be key to developing a successful vaccine strategy for the virus. Read MoreJun 8, 2018
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Enzyme protects against obesity-related heart disease
Vanderbilt scientists have discovered that a certain enzyme plays a crucial role in preventing obesity-related cardiac dysfunction. Read MoreJun 7, 2018
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Evolution of a deadly virus
Genomic sequences have revealed that Florida is a major source of a mosquito-borne virus that causes disease in horses and humans. Read MoreMay 23, 2018
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New target to stop Ebola
A new Vanderbilt study suggests it may be possible to develop antibody therapies or a universal vaccine effective against multiple Ebola virus family members. Read MoreMay 21, 2018
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Shaping reward circuits
Using techniques to control and monitor the activities of individual neurons, Vanderbilt investigators are probing the brain’s reward circuitry. Read MoreMay 18, 2018
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Alphavirus “Achilles heel”
Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses. Read MoreMay 17, 2018
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Launch event helps introduce ‘All of Us’ initiative to Nashville
On Sunday, May 6, Nashville played an important role in the nationwide launch of “All of Us,” the National Institutes of Health’s (NIH) research program that aims to collect the health information of 1 million or more research participants. Read MoreMay 10, 2018
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VUMC plays major role in nationwide ‘All of Us’ program
In 1969 the United States was the first nation to land a man on the moon. Forty-nine years later this country is poised to take another “giant leap” for humankind, this time by unleashing a revolution in medical research and human health. Read MoreMay 10, 2018
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Putting the brakes on sepsis
An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection. Read MoreMay 9, 2018
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Records point to drug-drug interaction
Patients who take a cholesterol-lowering statin drug while taking the antibiotic daptomycin have increased risk of developing muscle weakness or a more severe form of muscle damage. Read MoreMay 7, 2018
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New breast cancer targets
A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer. Read MoreMay 4, 2018
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Understanding HDL structure
Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function. Read MoreMay 3, 2018
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Wilkins takes key role in national ‘All of Us’ precision medicine effort
Consuelo Wilkins, MD, MSCI, has played a major role in the development of the national All of Us Research Program, an ambitious effort led by the National Institutes of Health (NIH) to accelerate the prevention and treatment of illness through precision medicine. Read MoreApr 26, 2018
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Gene expression in mitral valve disease
A protease gene family may be new targets for treating mitral valve disease, which causes blood to flow backwards in the heart. Read MoreApr 25, 2018
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Unraveling genetic mystery next step in Zika and dengue fight
How a bacteria hijacked insect fertility remained a mystery for five decades, until Associate Professor of Biological Sciences Seth Bordenstein and his team helped solve it. Read MoreApr 23, 2018
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Toxin floats on lipid rafts
The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read MoreApr 23, 2018