NIH
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Cell-cell signals in developing heart
Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease. Read MoreJun 10, 2019
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Mouth health and colorectal cancer
Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC. Read MoreJun 6, 2019
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Study details regulation of a multi-drug transporter
Vanderbilt University researchers have discovered how a protein pump distinguishes between chemicals that it will expel from a cell and inhibitors that block its action. The new findings could guide the development of more efficient inhibitors to prevent cancer cell resistance to chemotherapy. Read MoreMay 30, 2019
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Frog fungus fights back
Louise Rollins-Smith and colleagues have discovered a new way that a deadly fungus evades frogs' immune systems. Read MoreMay 15, 2019
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Dynamic basement membranes
Basement membranes are important structural and functional components of tissues. New research provides insight into how they repair themselves. Read MoreMay 9, 2019
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Blueprint for rebuilding the heart
New findings may speed progress toward programming cells to rebuild damaged hearts more quickly. Read MoreMay 9, 2019
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Researchers find high-risk genes for schizophrenia
Using a unique computational framework they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute has identified 104 high-risk genes for schizophrenia. Read MoreApr 18, 2019
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Indicators of despair rising among Gen X-ers entering middle age
In 2016, a surprising decline in life expectancy was ascribed to "deaths of despair" among working-class middle-aged white men displaced by a changing economy. However, new research shows indicators of despair are rising among Americans approaching middle age regardless of race, education and gender. Read MoreApr 15, 2019
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How bugs overcome host defenses
Eric Skaar and colleagues have figured out how a common bug responsible for ventilator-associated pneumonia responds when starved of zinc, a metal it needs to survive, which may lead to new therapeutic targets for the dangerous infection. Read MoreApr 12, 2019
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Discovery aids search for cancer biomarkers
A report by researchers at Vanderbilt University Medical Center has shattered conventional wisdom about how cells, including cancer cells, shed DNA into the bloodstream. Read MoreApr 12, 2019
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The arrestin-GPCR connection
Vsevolod Gurevich and colleagues have discovered new insights into arrestin proteins, which turn off a cell's environmental message "inbox." Read MoreApr 12, 2019
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Pathways of radiosensitization
Austin Kirschner and colleagues are learning more about how the cancer drug enzalutamide combines with radiation therapy to treat difficult prostate tumors. Read MoreApr 12, 2019
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Webinar on engaging with federal government for early career researchers is April 15
An April 15 webinar designed for early career investigators will highlight opportunities at key agencies such as the National Institutes of Health, National Science Foundation and Department of Defense. The event will be from noon to 1 p.m. in the Baker Building, Room 800C. Read MoreApr 7, 2019
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Drug interaction causes hypotension
A commonly used muscle relaxant can cause severely low blood pressure in patients already taking a CYP1A2 inhibitor, such as ciprofloxacin, find Cecilia Chung and colleagues. Read MoreApr 4, 2019
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Cardiac dysfunction in Duchenne’s
Jonathan Soslow and colleagues have found more clues to why people with Duchenne muscular dystrophy are at risk for a certain kind of heart problem. Read MoreApr 4, 2019
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Cancer prevention drug also disables H. pylori bacterium
A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered. Read MoreMar 28, 2019
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Study aims to predict treatment response in epilepsy patients
Vanderbilt researchers are on a quest to develop early biomarkers of treatment outcomes for patients with temporal lobe epilepsy based on their individual brain networks. Read MoreMar 14, 2019
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Reprogramming cells for kidney repair
Lauren Woodard and Matthew Wilson have discovered a way to reprogram adult human kidney cells into cells similar to those that form during embryonic development, which could lead to new kidney disease treatments. Read MoreMar 14, 2019
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Exploring the brain’s white matter
Though neurological activity is generally associated with the brain's gray matter, Muwei Li and colleagues have now measured it in white matter as well. Read MoreMar 14, 2019
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Correctly copying DNA
New research into the enzyme topoisomerase II sheds light on how it helps DNA replicate properly. Read MoreMar 14, 2019