NCI
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Genetics of lung cancer survival
Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans. Read MoreJun 29, 2017
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STINGing combination for cancer
A novel immunotherapy combination induced remarkable regression of tumors in a mouse model of head and neck cancer. Read MoreJun 19, 2017
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PET imaging to predict tumor response
A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models. Read MoreJun 14, 2017
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Repriming replication roadblocks
New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away. Read MoreJun 12, 2017
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Nanobeacon lights up colon tumors
A novel fluorescent nanobeacon can distinguish normal from diseased colon tissue, potentially offering advantages for colorectal cancer screening. Read MoreMar 30, 2017
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New target for colorectal cancer
Vanderbilt investigators have discovered that activated epidermal growth factor receptor may be a target for therapies to prevent colorectal cancer development. Read MoreMar 17, 2017
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Esophageal cancer complexities
New findings that reveal complex interactions in esophageal adenocarcinoma could lead to diagnostic, prognostic or therapeutic biomarkers. Read MoreMar 16, 2017
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Role for mouth microbes in diabetes?
A higher abundance of certain bacterial species in the mouth appears to reduce the risk of type 2 diabetes, Vanderbilt investigators have discovered. Read MoreMar 8, 2017
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Investigators seek new way to define cell identity
Vanderbilt researchers hope their new method to describe cells will be widely adopted and used to generate a “Who’s Who” database of cell types. Read MoreMar 2, 2017
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Improving therapies for GI tumors
A signaling protein overexpressed in upper gastrointestinal cancers is an attractive therapeutic target. Read MoreFeb 20, 2017
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New target for chronic infection
An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered. Read MoreFeb 2, 2017
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Flu vaccine response in older adults
High dose flu vaccine boosts the immune response in older adults by increasing activation of certain immune cells. Read MoreJan 25, 2017
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Colorectal cancer clues
Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways. Read MoreJan 19, 2017
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Metastatic pancreatic cancer ‘reprograms’ for malignancy
Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. Read MoreJan 19, 2017
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Midgut neuroendocrine tumor prognosis
Vanderbilt investigators recommend that the presence of tumor deposits in the abdomen be included when staging midgut neuroendocrine tumors. Read MoreJan 6, 2017
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Single-cell analysis of solid tumors
A new method will make it possible to study solid tumors and healthy tissues using mass cytometry. Read MoreDec 12, 2016
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Protecting the blood-brain barrier
Vanderbilt investigators have discovered how a promising cancer immunotherapy causes brain swelling, findings that could lead to ways to protect brain function while fighting cancers. Read MoreDec 9, 2016
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A DARPP role in gastric cancer
Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies. Read MoreNov 3, 2016
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Single-cell study of tumor samples
A new method for analyzing cells in fixed biopsy tissues from patients by guide personalized treatment strategies for cancer. Read MoreOct 26, 2016
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DNA damage response protein
Vanderbilt researchers have determined that a previously uncharacterized protein responds to DNA replication stress and has an essential role in maintaining the integrity of the genome. Read MoreOct 21, 2016