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NCI Archives

Probing H. pylori cancer protein

Feb. 15, 2019—Timothy Cover, john Loh and colleagues have identified how a certain type of mutation influences the risk of premalignant and malignant changes in the stomach.

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Building a pancreas

Jan. 17, 2019—Ken Lau and Guoqiang Gu have identified a critical biomarker in determining how a pancreatic progenitor cell will develop.

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Breast cancer-killing RIG

Dec. 19, 2018—New research led by Rebecca Cook demonstrates that an antiviral receptor called RIG-I has potent immunogenic and therapeutic effects in breast cancer.

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Green tea and diabetes

Nov. 30, 2018—A recent study led by Xiao-Ou Shu and colleagues found that green tea drinking was associated with increased risk of type 2 diabetes in Chinese adults, possibly due to the use of pesticides on tea plants--though the researchers call for further study of the exact mechanism.

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Analyzing single-cell landscapes

Nov. 30, 2018—Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies.

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Immunotherapies linked to specific heart complications

Nov. 16, 2018—In the first large-scale analysis of cardiovascular complications linked to immune checkpoint inhibitors, Vanderbilt researchers have identified several of the conditions that arise and have determined that they usually appear early in treatment.

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Team’s findings show glutamine metabolism affects T cell signaling

Nov. 1, 2018—Jeffrey Rathmell and colleagues show that a drug that inhibits glutamine metabolism — currently in clinical trials as an anticancer agent — might also be useful as a treatment for inflammatory and autoimmune diseases.

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Studying cellular deliveries

Oct. 26, 2018—James Patton and colleagues have demonstrated how colon cancer cells transmit genetic data to other cells.

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Grant enhances study of new chemotherapy targets

Oct. 19, 2018—Vanderbilt chemists have been awarded $7.2 million over the next five years from the National Cancer Institute to lead an initiative to better understand how a combination chemotherapy for breast cancer targets DNA.

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Diabetes drug may prevent liver cancer

Sep. 21, 2018—A new study by Harvey Murff finds that diabetics who take metformin have lower rates of liver cancer than those who take other diabetes drugs.

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New histoplasmosis risk map

Sep. 21, 2018—Stephen Deppen and colleagues have developed an updated map showing new areas of increased risk for a common lung infection.

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Study tracks incidence, timing of immunotherapy-related deaths

Sep. 13, 2018—Researchers led by melanoma researcher Douglas Johnson have answered questions about the incidence and timing of rare but sometimes fatal reactions to the most widely prescribed class of immunotherapies.

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