• Vanderbilt University

    Mechanism of a DNA repair protein

    Vanderbilt investigators have discovered details about the mechanism of an important DNA repair protein that maintains genome stability. Read More

    Apr. 15, 2016

  • Vanderbilt University

    Switching breast cancer off

    Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets. Read More

    Apr. 14, 2016

  • Vanderbilt University

    Pietenpol named to NCI Blue Ribbon Panel

    Jennifer Pietenpol, Ph.D., B.F. Byrd Jr. Professor of Oncology and director of Vanderbilt-Ingram Cancer Center (VICC), has been selected to serve on a Blue Ribbon Panel that will inform the scientific direction and goals at the National Cancer Institute (NCI) for Vice President Joe Biden’s National Cancer Moonshot Initiative. Read More

    Apr. 7, 2016

  • DNA sequence visualization

    New role identified for p73 gene

    The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility. Read More

    Apr. 1, 2016

  • Vanderbilt University

    Cancer prevention and poverty

    A new epidemiological study supports smoking cessation and avoidance of sedentary lifestyle as cancer prevention measures. Read More

    Mar. 31, 2016

  • Vanderbilt University

    ROCKs and cancer invasion

    The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies. Read More

    Mar. 17, 2016

  • Vanderbilt University

    Melanoma response to immune therapy

    Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read More

    Mar. 3, 2016

  • Vanderbilt University

    Combining treatments for melanoma

    Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients. Read More

    Feb. 18, 2016

  • Vanderbilt University

    Overcoming lung cancer drug resistance

    Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients. Read More

    Feb. 10, 2016

  • VICC joins other major cancer centers in HPV vaccine campaign

    VICC joins other major cancer centers in HPV vaccine campaign

    In response to low national vaccination rates for the human papillomavirus (HPV), Vanderbilt-Ingram Cancer Center (VICC) has joined 68 of the nation’s other NCI-designated cancer centers in recommending increased HPV vaccination for the prevention of cancer. Read More

    Feb. 4, 2016

  • x-ray of lungs with a suspicious spot highlighted in red

    Study identifies new culprit in lung cancer development

    A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, Vanderbilt University investigators have discovered. Read More

    Jan. 27, 2016

  • Vanderbilt University

    Wound-healing scaffolds

    The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring. Read More

    Jan. 27, 2016

  • model of DNA double helix

    Faulty building blocks in DNA

    An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations. Read More

    Jan. 22, 2016

  • Vanderbilt University

    Copying chromosome caps

    Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports. Read More

    Jan. 8, 2016

  • Vanderbilt University

    DISSECTing cell signaling networks

    Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution. Read More

    Dec. 14, 2015

  • Vanderbilt University

    New lead for ovarian cancer treatment

    Combining inhibitors of the BMP signaling pathway with standard chemotherapy drugs may overcome drug resistance in ovarian cancer. Read More

    Dec. 10, 2015

  • Vanderbilt University

    VICC’s Horn lands Team Leadership Award from NCI

    Leora Horn, M.D., M.Sc., associate professor of Medicine and clinical director of the Thoracic Oncology Program at Vanderbilt-Ingram Cancer Center (VICC), has received a 2015 Cancer Clinical Investigator Team Leadership Award (CCITLA) from the National Cancer Institute (NCI). Read More

    Nov. 19, 2015

  • Vanderbilt University

    Immune system a must for kidney repair

    A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells. Read More

    Nov. 12, 2015

  • DNA sequence visualization

    Study helps clarify components of DNA ‘copy machine’

    Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery. Read More

    Nov. 12, 2015

  • Vanderbilt University

    Detect and defend against pathogens

    Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections. Read More

    Nov. 4, 2015