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DNA Archives

Novel insights to antibiotic targets

Sep. 29, 2017—New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.

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Health and Medicine Reporter Research


Deciphering potent DNA toxin’s secrets

Aug. 1, 2017—Vanderbilt researchers uncover the secret of the remarkable potency of the DNA toxin yatakemycin, which could someday be harnessed to fight cancer.

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Life, Earth and Space Research


New method for tapping vast plant pharmacopeia to make more effective drugs

Apr. 14, 2017—Geneticists have developed an effective new method for identifying the genes that produce the chemicals plants use to protect themselves from predators, which are an important natural drug source.

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Life, Earth and Space Research


Team identifies ‘switch’ involved in DNA replication  

Feb. 23, 2017—DNA replication is an extraordinarily complex multi-step process that makes copies of the body’s genetic blueprint. It is necessary for growth and essential to life. Now researchers at the California Institute of Technology (Caltech) and Vanderbilt University have found evidence that one of those steps may involve the telephone-like transmission of electrical signals regulated by a chemical “switch.”

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Health and Medicine Reporter Research


Saliva test for obesity risk

Jan. 24, 2017—“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity.

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Health and Medicine Reporter Research


DNA duplicator small enough to hold in your hand

Jan. 11, 2017—Imagine a “DNA photocopier” small enough to hold in your hand that could identify the bacteria or virus causing an infection even before the symptoms appear.

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DNA duplicator small enough to hold in your hand

Jan. 11, 2017—Vanderbilt engineers have developed a new method for duplicating DNA that makes devices small enough to hold in your hand that are capable of identifying infectious agents before symptoms appear.

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Engineering and Technology Research


Rheumatoid subtypes explored by PheWAS

Oct. 7, 2016—A computer-based method pioneered at Vanderbilt is being used to compare subtypes of rheumatoid arthritis.

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Health and Medicine Reporter Research


Discovery of male-harming DNA mutation reinforces ‘mother’s curse’ hypothesis

Aug. 2, 2016—There is new evidence that the "mother’s curse" – the possibility that moms may transmit genes to their children that harm their sons but not their daughters – holds true in animals.

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Life, Earth and Space Research


When mitochondrial genes act up

Jul. 12, 2016—A team of Vanderbilt scientists have identified some of the methods that mutant mitochondrial DNA use to circumvent the molecular mechanisms that cells use to regulate mitochondrial activity.

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Mechanism of a DNA repair protein

Apr. 15, 2016—Vanderbilt investigators have discovered details about the mechanism of an important DNA repair protein that maintains genome stability.

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Health and Medicine Reporter Research


Neanderthal DNA has subtle but significant impact on human traits

Feb. 11, 2016—The first study that directly compares Neanderthal DNA in the genomes of a significant population of adults of European ancestry with their clinical records confirms that this archaic genetic legacy has a subtle but significant impact on modern human biology.

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