Department Of Veterans Affairs

It might be possible to generate a “metabolically healthy” state of obesity by targeting signaling pathways that improve insulin sensitivity. Read More

Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes. Read More

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies. Read More

Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer. Read More

In the latest VUCast: ICU patients are leaving hospitals with a dementia-like disease; What’s the fate of the Republican Party?; Hear from Pulitzer Prize-winning author and Distinguished Visiting Professor Jon Meacham; and It's time to celebrate -- the Rate My Professor 2013 rankings are in. All this and more in Vanderbilt’s online newscast. Watch now. Read More

Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer. Read More

A factor produced by most malignant cells can both promote and inhibit tumor growth – an insight that is critical to using cancer drugs developed to block this factor. Read More

A high-salt diet worsens the carcinogenic effects of Helicobacter pylori, a bacterium that colonizes the stomachs of half of the world’s population. Read More

An antioxidant enzyme also functions as a tumor suppressor to limit cancer development in the esophagus. Read More

An immune system factor associated with severe asthma may actually reduce asthma attacks induced by viral infections. Read More

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue. Read More

The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments. Read More

The kidney can mediate its own repair through proliferation of resident immune system cells. Read More

A rare genetic syndrome provides new clues to lung scarring (pulmonary fibrosis), a potentially deadly consequence of many lung diseases. Read More

Two newly identified gene variants linked to breast cancer may aid in predicting disease risk and targeting screening and prevention strategies. Read More

New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified. Read More

The spinal cord’s neuropeptide Y signaling pathway may be a good target for new pain therapeutics. Read More

A rare, inherited mutation confers an eightfold increased risk of prostate cancer, a recent study shows. Read More

Enhancing stem cell survival is key to improving cell-based therapies for regenerative medicine, and a new drug could help. Read More

Study suggests that the “kynurenine” biochemical pathway could be a target for reducing delirium and coma in critically ill patients. Read More