Charles Sanders
Arrhythmia culprit: supertrafficking ion channel
Apr. 15, 2021—Charles Sanders, PhD, and colleagues show how a “supertrafficking” mutant potassium channel contributes to heart rhythm abnormalities.
Despite limitations of pandemic, research continues in Basic Sciences, Blair
Feb. 10, 2021—During the Research Ramp-up process, more than 3,000 Vanderbilt research personnel have returned to in-person research activities, while many others have continued remotely through perseverance and ingenuity. The efforts of the School of Medicine Basic Sciences' Charles Sanders and Vanderbilt Blair School of Music's Jeremy Wilson are highlighted.
Vanderbilt-Ancora partnership advances research for Charcot-Marie-Tooth disease
Nov. 17, 2020—Further research by biochemistry professors Charles Sanders and Bruce Carter into therapeutics for Charcot-Marie-Tooth disease, an inherited condition that damages peripheral nerves, will be funded by Ancora Innovation LLC, a Deerfield Management company that supports Vanderbilt’s innovative life science research.
Vanderbilt researchers work to build a molecular Trojan horse to battle COVID-19
Nov. 17, 2020—Vanderbilt biochemists figure out how the little-understood Envelope protein helps SARS-CoV-2 function and how to disrupt the endogenously creative virus.
Vanderbilt biochemists reveal the cause of Charcot-Marie-Tooth disease—too much of a good thing
Oct. 27, 2020—Vanderbilt researchers—including Charles Sanders, associate dean for research and professor of biochemistry, and graduate student Justin Marinko—have illuminated the cause of Charcot-Marie-Tooth disease, putting them on the road to developing therapeutic approaches for the disease that affects one in 2,500 people.
Up Close and Personal: Vanderbilt explores the frontiers of imaging technology
Jun. 8, 2018—Recent advances in imaging technology are enabling Vanderbilt scientists to gain unprecedented views of how molecules, cells and tissues work together, yielding radical new insights into the causes, treatment and prevention of disease.
Long QT syndrome – revealed
Mar. 12, 2018—Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders.
Discovery sheds light on protein key to nerve cells’ myelin sheath
Aug. 17, 2017—Genetic mutations in PMP22 (peripheral myelin protein 22) cause a variety of peripheral neuropathies, underscoring the importance of the protein to a healthy peripheral nervous system. But the precise function of PMP22, a major component of the myelin sheath that surrounds and insulates peripheral nerve cell axons, has been unclear.
Protein structure may aid in treating Alzheimer’s disease
Apr. 27, 2017—A new protein structure may guide the development of Alzheimer's therapeutics.
Sanders named to key VUSM Basic Sciences role
Feb. 9, 2017—Charles Sanders, Ph.D., has been named associate dean for Research in the Basic Sciences of Vanderbilt University School of Medicine.
Surprising finding by VU team sheds light on fibrotic disease
Jan. 19, 2017—Integrins are membrane proteins made up of combinations of different “alpha” and “beta” subunits that enable cells throughout the body to interact with their surroundings.
Study reveals new clues to cystic fibrosis ‘gender gap’
Sep. 15, 2016—A research team led by structural biologists from Vanderbilt University has come up with the first detailed molecular explanation for a factor that may contribute to the so-called cystic fibrosis (CF) “gender gap.”