cancer
Blocking tumor ‘signals’ and ‘fuel’
Aug. 25, 2020—Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients.
A “torque” for tumor blood vessels
Aug. 20, 2020—Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies.
Study shows better option for treatment of inoperable anal cancer
Jun. 24, 2020—People with inoperable anal cancer treated with carboplatin-paclitaxel had fewer complications and lived longer than those who received another chemotherapy that has been more often administered.
Probing innate immunity
May. 19, 2020—Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.
Imaging breast cancer cell size
Feb. 10, 2020—A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy.
Cell fate signaling
Dec. 17, 2019—A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy.
Understanding cell division
Nov. 18, 2019—Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells.
On-the-move cancer cells prefer a “comfort cruise,” follow predictable paths of least resistance
Sep. 13, 2019—New research from a group of Vanderbilt biomedical engineers reveals that while cancer cells metastasize quickly, they generally choose pathways that use the least amount of energy.
A “rheostat” for cancer signals
Aug. 27, 2019—Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells.
Cancer susceptibility genes
Aug. 26, 2019—Gene variants associated with cancer risk appear to contribute to carcinogenesis by regulating target genes that in turn promote the generation of mutations.
Meet the alpacas that are helping researchers who study autism, Alzheimer’s and cancer
Aug. 13, 2019—Written by Heidi Hall Alpacas aren’t the typical animals that drivers spot as they wind their way through rural Tennessee, but there’s a happy herd of them outside Waverly, where they eat the finest pellets, walk up and down a scenic hill and potentially save lives. They’re owned by a team of Vanderbilt University researchers...
New window on fibrosis
Aug. 8, 2019—A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases.