Cancer
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New screening method could pave the way for future cancer drug discoveries
The laboratories of Brian Bachmann and Jonathan Irish have developed a method to discover new small molecules that may kill cancer cells by working through the body’s immune system. Read MoreJan 17, 2023
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Policy, resources crucial for lung cancer screening: study
Vanderbilt reseach shows that resources for lung cancer screening programs increased the number of veterans screened. Read MoreSep 29, 2022
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Lee named 2022 Innovation Fund investigator by The Pew Charitable Trusts
Ethan Lee, professor of cell and developmental biology and pharmacology, has been named a 2022 Innovation Fund investigator by The Pew Charitable Trusts. Read MoreSep 27, 2022
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Leveraging the structure of bacterial host cell receptors to detect cancer
Biomedical researchers open the door to new ways to detect cancer cells. Read MoreAug 16, 2022
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Research Snapshot: Researchers create algorithm to help predict cancer risk associated with tumor variants
Vanderbilt researchers have developed an active machine learning approach to predict the effects of tumor variants of unknown significance, or VUS, on sensitivity to chemotherapy. Characterizing VUS can maximize clinical care and precision medicine for each patient. Read MoreAug 9, 2022
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Studies combine genetic testing, electronic health records to find undiagnosed diseases
Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations. Read MoreApr 28, 2022
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Research Snapshot: Collaborative research lays groundwork for potential treatment of a rare and deadly type of cancer
A collaborative project between William Tansey and Stephen Fesik has laid the foundation for pre-clinical and clinical trials for rare childhood tumors that are diagnosed in 25 children per year in the United States. Read MoreApr 22, 2022
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‘Survivor’ winner discusses the intersections of cancer and mental health
Ethan Zohn, winner of CBS’s "Survivor," a two-time cancer survivor, humanitarian and former professional soccer player, will discuss his journey with reality television, cancer, mental health and humanitarian work on April 26 at 7 p.m. CT at the Blair School’s Ingram Hall. Read MoreApr 8, 2022
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Research Snapshot: Biologists discover signaling pathways potentially associated with pancreatic cancer
Vanderbilt and the Salk Institute collaborate on the development of a research “road map” that could lead to new ways to detect early signs of tumor formation. Read MoreMar 31, 2022
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Probing cancer cell invasion
The rigidity of the extracellular matrix that surrounds cells impacts the contractile and invasive properties of head and neck cancer cells. Read MoreMar 1, 2022
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Research Snapshot: Vanderbilt team discovers potential explanation for treatment resistance in skin cancer
Melanoma is the fifth most-common type of cancer in the U.S., and according to the American Cancer Society, about half of patients with malignant melanoma have mutations of the BRAF gene. Identification of potential tumor biomarkers such as SOX10 can help physicians better predict outcomes for their patients. Read MoreFeb 28, 2022
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Study of fully vaccinated patients with cancer who had breakthrough COVID-19 shows 13% mortality rate
New research finds that fully vaccinated patients with cancer who had breakthrough COVID-19 infections remained at high risk for hospitalization and death. Read MoreDec 24, 2021
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Immune landscape in adrenal cancer
The profile of immune-related gene expression and tumor-infiltrating immune cells in adrenocortical cancer suggests targets for new treatment strategies. Read MoreDec 14, 2021
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Research Snapshot: Sugar compounds in breast milk relieve uncomfortable side effects caused by chemotherapy
Steven Townsend, associate professor of chemistry, and Fang Yan, research professor of pediatrics and cell and development biology, have discovered how a sugar in human breast milk mitigates damage to the small intestines caused by chemotherapy-induced mucositis. Read MoreOct 4, 2021
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Research Snapshot: Researchers derive new cancer therapies to decrease the risk of heart damage
Following decades of worldwide research standstills on cancer drug improvement, Steven Townsend and his team of researchers synthesize cancer therapeutics that bypass toxicity aimed at heart health. Est. reading time: 2.5 minutes. Read MoreJul 29, 2021
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Prediction models for breast cancer
Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction. Read MoreJul 27, 2021
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Researchers discover that protein switches functions to regulate DNA replication
Vanderbilt biochemists have discovered that the protein RADX has different biological effects at sites of DNA synthesis, depending on the cellular conditions — even though it works the same way in both stressed and unstressed cells. Read MoreJul 22, 2021
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Chemo for cancer lowers dementia risk
Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people. Read MoreMar 22, 2021
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New CRISPR screening technique developed at Vanderbilt leads to discovery of pathway that may be linked to cancer initiation
A new genome-wide CRISPR screening technique conducted by researchers at Vanderbilt University is offering new insights about how tumors in 80 to 90 percent of all cancers grow. Read MoreMar 10, 2021
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A protein that can melt tumors discovered at Vanderbilt
For the second time, cancer researchers at Vanderbilt have discovered a protein that—when genetically manipulated to impede it from interacting with a gene responsible for cancer genesis—effectively melts tumors in days. Read MoreJan 27, 2021