Cancer

Kevin Murphy, Andrew W. Mellon Chair in the Humanities and professor of history of art and architecture, and Mary Anne Hunting, BA’80, have uncovered the histories of female architects in the American Modernism period of the U.S. in new research. Read More

Yi Ren’s most recent paper, published in eLife, describes the structure of a protein complex involved in mRNA export that sheds light on the underlying molecular mechanism of mRNA export and the role it plays during infection by herpes viruses. Read More

Vanderbilt researchers have developed a new nanoparticle that can more effectively get drugs inside of cells to boost the immune system and fight diseases like cancer. Read More

A multidisciplinary research team at Vanderbilt University and Vanderbilt University Medical Center has discovered a new way to kill a tumor by disrupting its acidic “microenvironment” without harming normal tissue. Read More

A multidisciplinary team of investigators has received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to support four closely linked projects exploring the fundamental mechanisms that drive the obesity-cancer connection, Read More

Vanderbilt engineering professor Justus Ndukaife is leading innovative research that more effectively traps nanosized extracellular vesicles and particles to analyze their roles in cancer, and neurodegenerative diseases. Read More

Vanderbilt researchers found that that T cells become “exhausted” within hours of encountering a tumor, challenging existing ideas about how T cells become dysfunctional. Read More

Vanderbilt researchers are bolstering the fight against cancer with technology that enhances the effectiveness of T cells that attack tumors. Read More

Fluorescent nanoparticles clearly identified colonic adenomas — precursors to colorectal cancer — in mice, and the formulation should translate to clinical use in humans. Read More

The laboratories of Brian Bachmann and Jonathan Irish have developed a method to discover new small molecules that may kill cancer cells by working through the body’s immune system. Read More

Vanderbilt reseach shows that resources for lung cancer screening programs increased the number of veterans screened. Read More

Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations. Read More

The rigidity of the extracellular matrix that surrounds cells impacts the contractile and invasive properties of head and neck cancer cells. Read More

New research finds that fully vaccinated patients with cancer who had breakthrough COVID-19 infections remained at high risk for hospitalization and death. Read More

The profile of immune-related gene expression and tumor-infiltrating immune cells in adrenocortical cancer suggests targets for new treatment strategies. Read More

Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction. Read More

Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people. Read More

William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth. Read More

Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women. Read More

Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients. Read More