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Basic Sciences Archives

What protein is that?

Mar. 28, 2018—An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research.

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Voluntary exercise and energy balance

Mar. 23, 2018—Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered.

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Founders’ Celebration for Institute of Chemical Biology set for March 28

Mar. 22, 2018—The Vanderbilt Institute of Chemical Biology (VICB) will hold a Founders’ Celebration mini-symposium on March 28 to acknowledge the contributions of its founders, Lawrence Marnett, PhD, and Ned Porter, PhD, and to celebrate 15-plus years of success as a trans-institutional scientific incubator.

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Study tracks protein’s role in stem cell function

Mar. 22, 2018—MCL-1 is a member of the BCL-2 family of proteins important for blocking apoptosis, or programmed cell death. Many types of cancer cells escape the body’s effort to kill them by overexpressing MCL-1.

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New imaging approach offers unprecedented views of staph infection

Mar. 15, 2018—A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state.

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Boehringer Ingelheim and Vanderbilt University expand partnership to develop novel treatment approaches for cancer

Mar. 14, 2018—New agreement will pursue therapies targeting MCL1 (myeloid cell leukemia 1), which is highly prevalent in many difficult-to-treat cancers.

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Long QT syndrome – revealed

Mar. 12, 2018—Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders.

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Iron-sulfur “intersection”

Mar. 8, 2018—Vanderbilt researchers have discovered an unanticipated link between sulfur and iron balance, pointing to a genetic basis for iron-deficiency anemia.

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VICC study sheds new light on Von Hippel-Lindau syndrome

Mar. 8, 2018—Investigators at Vanderbilt-Ingram Cancer Center (VICC) and the Virginia Tech Carilion Research Institute (VTCRI) have revealed a gene mutation’s role in Von Hippel-Lindau syndrome, a genetically inherited disease which causes tumor growth in several organs.

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Lovly earns scholarship grant for lung cancer research

Mar. 8, 2018—Christine Lovly, MD, PhD, assistant professor of Medicine at Vanderbilt, has received a $200,000 grant to support promising new research on lung cancer.

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Mitochondrial mutations and disease

Feb. 22, 2018—New findings suggest that oxidative stress damages mitochondrial DNA, and they link this damage to a disease state.

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Linda Sealy receives 2018 AAAS Mentor Award for Lifetime Achievement

Feb. 15, 2018—Professor Linda Sealy has won the AAAS Mentor Award for Lifetime Achievement for her continued efforts to increase the number of underrepresented minorities in STEM Ph.D. programs.

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