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Basic Sciences

Insights on diabetic retinopathy

Jan. 23, 2020—A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report.

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Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

Jan. 13, 2020—An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

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Structural views of a C. diff toxin

Jan. 10, 2020—D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.

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Cell fate signaling

Dec. 17, 2019—A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy.

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Protein dynamics in the beating heart

Dec. 16, 2019—To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction.

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Enabling Innovation seminar: ‘Attracting Capital to Fuel Your Biotech/Scientific Startup’ Dec. 13

Dec. 9, 2019—The Enabling Innovation Initiative presents Kayla Graff, CEO and co-founder of SweetBio, who will discuss “Million Dollar Lessons: Attracting Capital to Fuel Your Biotech/Scientific Startup” on Friday, Dec. 13, beginning at 2 p.m. in Light Hall, Room 512.

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Study reveals mysteries of critical brain receptor complex

Dec. 5, 2019—Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.

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Genetic screen in worms reveals critical step in insulin synthesis

Dec. 4, 2019—The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes.

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Understanding cell division

Nov. 18, 2019—Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells.

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Blueprint for treating epilepsy

Nov. 14, 2019—Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders.

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Discovery Science Emerging Scholars Lecture: Reginald Cannady Nov. 12

Nov. 1, 2019—Reginald Cannady, a postdoctoral research fellow at the Medical University of South Carolina, will discuss “Probing Novel Targets to Reduce Heavy Drinking in Models of Alcohol Use Disorder” at 4 p.m. Tuesday, Nov. 12, in Light Hall, Room 512, as part of the Discovery Science Emerging Scholars Lecture Series.

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Vanderbilt investigators lead effort to create map of the human kidney

Nov. 1, 2019—Researchers at Vanderbilt's Biomolecular Multimodal Imaging Center are working to create a high-resolution, three-dimensional “atlas” of the human kidney that will help future researchers understand what exactly goes wrong when kidneys fail.

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