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Basic Sciences

Loss of ‘Jedi’ alters neuron activity

Mar. 10, 2020—This is not the Jedi you're thinking of. This Jedi is a receptor that helps clear away dead neurons during development, and its loss changes the activity of dorsal root ganglia neurons, which could have implications for treating chronic pain.

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CANCELED: Basic Sciences Mental Health and Wellness Summit set for March 17

Mar. 6, 2020—Vanderbilt Basic Sciences will host a Mental Health and Wellness Summit on Tuesday, March 17, featuring keynote addresses for faculty and staff and for graduate students and postdoctoral scholars by Sharon Milgram, director of the National Institutes of Health Office of Intramural Training and Education.

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Clues to lung injury in preterm babies

Mar. 5, 2020—Jennifer Sucre and colleagues have discovered a factor that contributes to the pathological changes of bronchopulmonary dysplasia, the most common complication of preterm birth.

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Faculty named to Global Voices Fellowship for fall 2020

Feb. 21, 2020—Erin Calipari, Kelly Haws and Marybeth Shinn have been selected as Global Voices Fellows for the fall 2020 semester.

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Protein interactions and brain function

Feb. 20, 2020—Roger Colbran and colleagues have discovered new molecular details about the function of an enzyme with a key role in shaping learning and memory.

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Transporter mutation alters cell energy

Feb. 20, 2020—A disease-associated mutation in a transporter protein causes cells to increase energy production, as if they are starving, Vanderbilt researchers have discovered.

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A key to calcium signaling

Feb. 11, 2020—Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles.

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Stanley Cohen, Vanderbilt biochemist who won Nobel Prize, has died

Feb. 6, 2020—Stanley Cohen, a legendary Vanderbilt University biochemist who was awarded the Nobel Prize for the discovery of epidermal growth factor and its receptor, died on Feb. 5 at the age of 97.

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New tool probes gene regulation

Feb. 6, 2020—Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation.

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A new contributor to atherosclerosis

Jan. 27, 2020—Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis.

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Insights on diabetic retinopathy

Jan. 23, 2020—A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report.

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Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

Jan. 13, 2020—An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

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