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Basic Sciences Archives

Predictive models for gene regulation

Aug. 17, 2018—Modern statistical tools are not very accurate when it comes to predicting the discrete and non-symmetric behaviors of individual cells. Gregor Neuert and colleagues say that's because the wrong tools are being used.

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Repairs in the basement membrane

Aug. 9, 2018—New research by Andrea Page-McCaw shows that a membrane that wraps around most animal tissues can heal within 24 hours, but does leave a scar.

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Genetic balancing act

Aug. 9, 2018—David Cortez and colleagues have found that a protein called RADX helps modulate a protein called RAD51 in order to make sure exactly the correct amount of DNA repair occurs.

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Vanderbilt Summer Science Academy holds 16th annual Student Research Symposium

Aug. 6, 2018—The Office of Biomedical Research Education and Training hosted the 16th annual Student Research Symposium, the culmination of more than 100 undergraduate students’ summer research experiences as part of the elite Vanderbilt Summer Science Academy.

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Enzyme helps build motor that drives neuron death

Aug. 6, 2018—The process, discovered in the axons of neurons, is implicated in Alzheimer’s, amyotrophic lateral sclerosis, traumatic brain injury and other diseases or injuries to the nervous system.

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Three VU doctoral students receive 2018 Gilliam Fellowships for Advanced Study

Aug. 1, 2018—The Howard Hughes Medical Institute has awarded 2018 Gilliam Fellowships for Advanced Study—created to ensure that a diverse and highly trained workforce is prepared to assume leadership roles in the sciences—to three Vanderbilt University doctoral students and their advisers.

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Fueling the MATE transporter

Jul. 20, 2018—In new research, Hassane Mchaourab and colleagues have uncovered new insights into drug resistance that could lead to the development of new anti-cancer and antibacterial drugs.

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SMAD4 clue to colon cancer

Jul. 5, 2018—Chronic inflammation is a predisposing condition for colorectal cancer, the third leading cause of cancer-related deaths in the United States. Anna Means, Ph.D., and colleagues have now linked inflammation-driven carcinogenesis in the colon to loss of an important signaling protein called SMAD4.

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Scavengers “protect” HDL

Jun. 29, 2018—Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease.

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Roden’s circulatory diseases research honored

Jun. 21, 2018—Vanderbilt University’s Dan Roden, MD, internationally known for his contributions to understanding how genetic variation affects drug response, has been named a recipient of the 2018 Louis and Artur Lucian Award for Research in Circulatory Diseases by McGill University in Montreal, Canada.

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Confronting TB resistance

Jun. 11, 2018—Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis.

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$8.1 million grant funds new center to research highly aggressive form of lung cancer

Jun. 8, 2018—A five-year National Cancer Institute grant will fund an interdisciplinary research center for the study of small cell lung cancer, a highly aggressive, incurable form of the disease.

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