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Basic Sciences Archives

How the skin protects

Apr. 19, 2018—Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier.

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Characterizing ‘keyhole’ is first step to fighting obesity at the cellular level

Apr. 18, 2018—A Vanderbilt team and their international colleagues characterized for the first time a complex, little-understood cellular receptor type that, when activated, shuts off hunger.

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“Idling” cancer cells may return

Apr. 11, 2018—Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment.

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New view of the heartbeat

Apr. 6, 2018—Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias.

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‘Collaborating with industry to advance basic science research’ topic of April 6 talk

Apr. 4, 2018—The Center for Technology Transfer and Commercialization's Alan Bentley will discuss emerging initiatives at Vanderbilt to engage industry more effectively, and a team from Deerfield Management will explain its collaborative approach to working with premier academic institutions to catalyze early stage therapeutic development.

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Kathleen Gould wins SEC Faculty Achievement Award

Apr. 2, 2018—Kathleen Gould, Louise B. McGavock Professor of Cell and Developmental Biology, is Vanderbilt’s winner of the 2018 Southeastern Conference Faculty Achievement Award.

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What protein is that?

Mar. 28, 2018—An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research.

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Voluntary exercise and energy balance

Mar. 23, 2018—Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered.

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Founders’ Celebration for Institute of Chemical Biology set for March 28

Mar. 22, 2018—The Vanderbilt Institute of Chemical Biology (VICB) will hold a Founders’ Celebration mini-symposium on March 28 to acknowledge the contributions of its founders, Lawrence Marnett, PhD, and Ned Porter, PhD, and to celebrate 15-plus years of success as a trans-institutional scientific incubator.

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Study tracks protein’s role in stem cell function

Mar. 22, 2018—MCL-1 is a member of the BCL-2 family of proteins important for blocking apoptosis, or programmed cell death. Many types of cancer cells escape the body’s effort to kill them by overexpressing MCL-1.

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New imaging approach offers unprecedented views of staph infection

Mar. 15, 2018—A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state.

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Boehringer Ingelheim and Vanderbilt University expand partnership to develop novel treatment approaches for cancer

Mar. 14, 2018—New agreement will pursue therapies targeting MCL1 (myeloid cell leukemia 1), which is highly prevalent in many difficult-to-treat cancers.

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