Aliquots
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Disease-fighting antibody production
New research links nutrient-responsive cellular signaling to the antibody-mediated immune response. Read MoreApr 20, 2018
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How the skin protects
Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier. Read MoreApr 19, 2018
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“Idling” cancer cells may return
Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment. Read MoreApr 11, 2018
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Aqueous humor, microRNAs and glaucoma
New findings highlight microRNAs — molecules that regulate gene expression — that are differentially expressed in glaucoma and could be candidate biomarkers or targets for therapy. Read MoreApr 10, 2018
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New view of the heartbeat
Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias. Read MoreApr 6, 2018
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Lung diseases share molecular signature
Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention. Read MoreApr 5, 2018
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What protein is that?
An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research. Read MoreMar 28, 2018
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Alzheimer’s proteins in ICU survivors
The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered. Read MoreMar 27, 2018
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Voluntary exercise and energy balance
Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered. Read MoreMar 23, 2018
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Kidney disease imaging
Making multiple measurements with MRI can provide comprehensive information about the molecular and cellular changes caused by kidney injury. Read MoreMar 22, 2018
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Botox for the shaky voice
Vanderbilt investigators found that Botox injection into the vocal cords can lead to improved quality of life for patients with voice muscle problems. Read MoreMar 14, 2018
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Long QT syndrome – revealed
Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders. Read MoreMar 12, 2018
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Brain connections in schizophrenia
Brain imaging studies have implicated the connection between two brain regions in the pathophysiology of schizophrenia. Read MoreMar 9, 2018
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Iron-sulfur “intersection”
Vanderbilt researchers have discovered an unanticipated link between sulfur and iron balance, pointing to a genetic basis for iron-deficiency anemia. Read MoreMar 8, 2018
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Structure of a stem cell niche
Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies. Read MoreFeb 28, 2018
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Cannabis compound reduces seizures
Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found. Read MoreFeb 26, 2018
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Hope for an RSV vaccine
Newly discovered features in an RSV protein may be useful for rational structure-based vaccine design. Read MoreFeb 23, 2018
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Mitochondrial mutations and disease
New findings suggest that oxidative stress damages mitochondrial DNA, and they link this damage to a disease state. Read MoreFeb 22, 2018
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A new target for neuroblastoma
Vanderbilt investigators have discovered that a sirtuin protein has oncogenic properties in neuroblastoma cells — and that blocking it reduces their growth and tumor-like characteristics. Read MoreFeb 14, 2018
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Cognition in rare hormonal disorder
Vanderbilt investigators have conducted the first systematic evaluation of cognitive function in children with a rare genetic disorder. Read MoreFeb 13, 2018