Health And Medicine
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A connection to schizophrenia
The insula, a small region of the brain involved in diverse brain functions had widespread dysconnectivity in schizophrenia, Vanderbilt researchers found. Read MoreJun 23, 2020
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Single mutation causes seizure disorder
A single mutation in one gene can impair inhibitory signaling in the brain and cause multiple types of seizures and behavioral abnormalities. Read MoreJun 22, 2020
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Major U.S. trial closes showing no benefit for hydroxychloroquine in COVID-19
The Outcomes Related to COVID-19 Treated with Hydroxychloroquine among In-patients with Symptomatic Disease (ORCHID) trial stopped enrolling new patients based on the fourth scheduled interim analysis showing no evidence of benefit or harm. Read MoreJun 21, 2020
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Probing DNA damage repair
After discovering a new mechanism for DNA damage repair last year, Vanderbilt biochemists now provide direct evidence for how it works. Read MoreJun 18, 2020
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Studying cells in reduced dimensions
Vanderbilt cell biologists have developed an unbiased, quantitative framework for evaluating single-cell data. Read MoreJun 18, 2020
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All of Us program launches cloud-based research platform
On May 27, the All of Us Research Program launched the beta version of its cloud-based research platform, the Researcher Workbench. Read MoreJun 18, 2020
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Vanderbilt researcher Houra Merrikh named a finalist of the 2020 Blavatnik National Awards for Young Scientists, inducted to New York Academy of Sciences
Biochemist Houra Merrikh has been named one of the nation’s rising stars in science for her work to reverse antimicrobial resistance. Read MoreJun 17, 2020
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Vanderbilt University partners with ACADIA Pharmaceuticals to develop novel treatments for central nervous system disorders
Vanderbilt University’s Warren Center for Neuroscience Drug Discovery has entered into an exclusive worldwide licensing and collaboration agreement with San Diego-based ACADIA Pharmaceuticals Inc. to develop treatments for disorders like Alzheimer’s and schizophrenia. Read MoreJun 16, 2020
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Leader in Vanderbilt drug discovery efforts, Craig Lindsley named interim editor-in-chief of ACS Pharmacology & Translational Science
Craig Lindsley, William K. Warren, Jr. Chair in Medicine and university professor of biochemistry, chemistry and pharmacology, has been named interim editor-in-chief of the journal "ACS Pharmacology & Translational Science." Read MoreJun 12, 2020
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Robotic technology speeds arrhythmia gene classification
Vanderbilt University Medical Center investigators have used high-throughput robotic technology to rapidly study and classify variations in a gene linked to heart rhythm disorders and cardiac conditions. Read MoreJun 12, 2020
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Breast cancer vaccine research delivers promising results
Vanderbilt researchers have developed what appears to be a simple and promising treatment for breast cancer metastasis. Read MoreJun 11, 2020
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C.diff captures blood cell cofactor to build defensive shield
Vanderbilt University Medical Center scientists have identified a C. diff protein system that senses and captures heme (part of hemoglobin) to build a protective shield that fends off threats from our immune system and antibiotics. Read MoreJun 10, 2020
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Vanderbilt, AstraZeneca sign new COVID-19 antibody agreement
After evaluating the ability of more than 1,500 monoclonal antibodies to bind and neutralize the COVID-19 virus, SARS-CoV-2, in the laboratory, AstraZeneca signed an exclusive license to six candidate antibodies in Vanderbilt’s portfolio. Read MoreJun 9, 2020
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Staph’s activation of blood clotting
Staph bacteria may change the factor they use to activate blood clotting — to evade the immune response — a new study suggests. Read MoreJun 9, 2020
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Vanderbilt researcher finds COVID-19 pandemic shapes opportunities for radical change to the U.S. health care system
A new article from Jonathan Metzl details how COVID-19 has dramatically revealed the ways that institutionalized inequality and structural racism shape health, and provides recommendations for radical change to the U.S. health care system. Read MoreJun 4, 2020
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Protecting the injured kidney
Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it. Read MoreJun 4, 2020
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Potential new cancer target
Vanderbilt researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis. Read MoreJun 4, 2020
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Remdesivir helps reduce COVID-19 recovery time: study
The investigational antiviral drug remdesivir can shorten the time to recovery in adults hospitalized with COVID-19, according to preliminary results of a clinical trial published last month in The New England Journal of Medicine. Read MoreJun 4, 2020
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Multinational consortium reports COVID-19 impact on cancer patients
People with cancer sickened by COVID-19 have a crude death rate of 13%, according to the largest series of data released thus far from a multinational perspective. The data on more than 900 patients also revealed cancer-specific factors associated with increased mortality. Read MoreJun 3, 2020
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Diversity in chemistry professor’s lab creates opportunity, explores clues to Alzheimer’s
Renã Robinson, associate professor of chemistry, has been immersed in science-related activities and classes since she was a child. Today, she is leading a diverse lab of researchers, using chemistry to uncover clues surrounding Alzheimer’s disease. Read MoreJun 3, 2020