Leigh MacMillan

The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes. Read More

New findings show that fibrin, a protein that was thought to play a key role in fracture healing, is not required, shifting understanding of how fractures heal. Read More

Vanderbilt researchers are exploring how neuroblastoma tumors begin and progress, knowledge that could provide new treatments for this pediatric cancer. Read More

Drugs that target DNA damage improve ovarian cancer cell response to platinum chemotherapies, suggesting new therapeutic opportunities. Read More

Eric Skaar, Ph.D., MPH, the Ernest W. Goodpasture Professor of Pathology, has received a Scholar Award from the American Asthma Foundation (AAF). Read More

Compounds found in olives and olive oil have anticancer activity, which may contribute to the cancer preventive properties attributed to the Mediterranean diet. Read More

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients. Read More

Vanderbilt and Stanford investigators have discovered how a protein that's part of the DNA replication "machinery" helps cells tolerate DNA damage. Read More

Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action. Read More

A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair. Read More

Vanderbilt investigators report the first use of a specialized type of MRI to study the hippocampus in patients with schizophrenia. Read More

Two physicians from Vanderbilt University have been elected to membership in two of the nation’s oldest and most respected medical honor societies — the Association of American Physicians (AAP) and the American Society for Clinical Investigation (ASCI). Read More

Vanderbilt University investigators have identified a cellular receptor for a toxin from Clostridium difficile (“C. diff”) — the leading cause of hospital-acquired diarrhea in the United States. Read More

The enzyme alkaline phosphatase may provide a new therapeutic option for women at high risk of pregnancy complications due to bacterial toxin exposure. Read More

The NetGestalt computing portal integrates vast amounts of data to aid users in finding biologically and clinically relevant information. Read More

A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells. Read More

A novel mechanism could point to new therapies for a group of inherited diseases that share pathological features. Read More

The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered. Read More

Vanderbilt researchers have discovered a novel mechanism for the development of dendritic spines – sites of nerve cell communication. Read More

Vanderbilt researchers have discovered that profound defects exist in the integrity of structural RNA molecules in patients with relapsing remitting multiple sclerosis. Read More