Leigh MacMillan
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Genetics Institute director Cox set for next Discovery Lecture
Nancy Cox, Ph.D., founding director of the Vanderbilt Genetics Institute, will deliver the next Flexner Discovery Lecture on Thursday, Dec. 17. Read MoreDec 10, 2015
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Microtubules act as cellular ‘rheostat’ to control insulin secretion
Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell. Read MoreDec 3, 2015
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Lung diseases expert Garcia set for Discovery Lecture
Joe G.N. “Skip” Garcia, M.D., recognized for developing novel therapies for critically ill patients with acute inflammatory lung disease, will deliver the next Flexner Discovery Lecture on Thursday, Dec. 10. Read MoreDec 3, 2015
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VUMC’s Baganz honored by Society for Neuroscience
For her contributions to public communication, outreach and education about neuroscience, Nicole Baganz, Ph.D., a postdoctoral fellow in Pharmacology, received the 2015 Next Generation Award from the Society for Neuroscience. Read MoreNov 12, 2015
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Study helps clarify components of DNA ‘copy machine’
Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery. Read MoreNov 12, 2015
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Detect and defend against pathogens
Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections. Read MoreNov 4, 2015
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Prenatal folic acid and asthma
The timing of folic acid-containing prescription filling during pregnancy was associated with childhood asthma, according to a new Vanderbilt study. Read MoreOct 30, 2015
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Inflammation, obesity and diabetes
Vanderbilt study adds to the mounting role for inflammatory signaling in obesity. Read MoreOct 29, 2015
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Biomarker for intestinal tumors
A new marker could be useful for diagnosing and treating neuroendocrine tumors of the small intestines. Read MoreOct 21, 2015
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Potential target for lung cancer therapy
The glutamine transporter protein appears to contribute to the survival of lung cancer cells, suggesting it may be a useful diagnostic biomarker and target for therapies. Read MoreOct 5, 2015
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Collaboration seeks to develop new therapies for bone, other diseases
La Jolla Pharmaceutical Co. and Vanderbilt University have signed a research and license agreement covering Vanderbilt’s research program and intellectual property rights related to compounds that block bone morphogenetic protein (BMP) type-I receptors. The compounds have therapeutic potential in a broad range of diseases, including rare genetic disorders. Read MoreOct 1, 2015
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Tolerating a transplant
A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease. Read MoreOct 1, 2015
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Hochmair set for next Discovery Lecture
The co-creator of the world’s first microelectronic multi-channel cochlear implant — a device that provides sound signals to the brain in deaf individuals — will deliver the next Flexner Discovery Lecture. Read MoreOct 1, 2015
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Nerve cell remodelers
Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory. Read MoreSep 18, 2015
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Discovery Lecture explores health care cost controls
“There’s no magic bullet” to control rising health care costs in the United States, health law expert Timothy Jost, J.D., said during last week’s Flexner Discovery Lecture. Read MoreSep 17, 2015
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Immune cells and obesity
Understanding how macrophage immune cells accumulate in fat tissue and contribute to the pathology of obesity could lead to the development of novel therapeutics for metabolic disorders. Read MoreSep 8, 2015
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Vitamin C protects blood vessel lining
Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases. Read MoreSep 4, 2015
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Jost set for Sept. 10 Discovery Lecture
The Flexner Discovery Lecture Series kicks off this fall with a discussion of health care cost control. Timothy Jost, J.D., emeritus professor at the Washington and Lee University School of Law, will speak on Thursday, Sept. 10. Read MoreSep 3, 2015
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Framework for studying cell responses
Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease. Read MoreAug 26, 2015
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Brain circuitry in psychosis
Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions. Read MoreAug 21, 2015