Leigh MacMillan

Vanderbilt researchers show that two factors promote the repair of myelin, the nerve cell covering that deteriorates in diseases such as multiple sclerosis. Read More

Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease. Read More

A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease. Read More

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish. Read More

Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read More

Joseph Coyle, M.D., an expert in the neurobiology of serious mental illness, will deliver the next Flexner Discovery Lecture on Thursday, March 10. Read More

Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients. Read More

One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, Vanderbilt researchers have discovered. Read More

Vanderbilt researchers have developed a high-throughput assay that will aid in identifying new compounds to treat preterm labor or postpartum bleeding. Read More

Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease. Read More

Emery Brown, M.D., Ph.D., a noted anesthesiologist, neuroscientist and statistician, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 11. Read More

A family of proteins with critical roles in cell division, synaptic transmission and cell migration don’t all function the way scientists thought they did, according to two new studies led by Vanderbilt researchers. Read More

A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, Vanderbilt University investigators have discovered. Read More

The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring. Read More

Roderick Little, Ph.D., a statistician with expertise in the analysis of data sets with missing values, will deliver the next Flexner Discovery Lecture on Thursday, Jan. 28. Read More

A team of Vanderbilt investigators developed a new method for rapidly generating heart muscle cells from stem cells. Read More

Vanderbilt investigators have identified a new biomarker to assess platelet function. Read More

Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports. Read More

Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis. Read More

Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution. Read More