Leigh MacMillan

James Allison, PhD, whose work led to the development of cancer immunotherapies known as “checkpoint inhibitors,” will deliver the next Flexner Discovery Lecture on Thursday, March 8. Read More

Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies. Read More

Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found. Read More

A clinical trial of an intervention for sepsis in patients in Zambia, led by Vanderbilt investigators, topped the list of 2017 trials featured by the website The Bottom Line. Read More

Vanderbilt investigators have discovered that a sirtuin protein has oncogenic properties in neuroblastoma cells — and that blocking it reduces their growth and tumor-like characteristics. Read More

Vanderbilt investigators have conducted the first systematic evaluation of cognitive function in children with a rare genetic disorder. Read More

Acetaminophen may offer a simple treatment to prevent tissue injury following lung transplant, Vanderbilt researchers have discovered. Read More

Bruce Gelb, MD, an expert on congenital heart defects, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 8. Read More

Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines. Read More

Vanderbilt researchers have discovered imaging features associated with increased risk for aggressive meningiomas (tumors of the brain membranes) that could help guide surgical planning and patient counseling. Read More

Vanderbilt investigators examined the entire training pathway of potential biomedical research faculty and found two key points of loss: during undergraduate education and in transition from postdoctoral fellowship to tenure-track faculty. Read More

A new report issued by the Blue Ridge Academic Health Group calls clinician burnout a “hidden epidemic” and suggests that addressing it should be one of the highest priorities across the healthcare industry. Read More

Vanderbilt researchers have discovered that curcumin — the active ingredient in the spice turmeric — needs to be metabolically activated to exert anti-inflammatory effects. Read More

A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease. Read More

New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition. Read More

The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years. Read More

To develop strategies for preventing radiation-induced lung fibrosis (scarring), Vanderbilt investigators are exploring the cell types and factors that contribute to the fibrotic response. Read More

Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension. Read More

Using super-resolution microscopy tools in the Nikon Center of Excellence, Vanderbilt investigators have determined the molecular architecture of the contractile ring machinery that functions during cell division — a process that is essential for life. Read More

Pediatric cardiologist James Johns, M.D., relishes being a physician who wears many hats. Read More