Vanderbilt Center For Structural Biology
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Molecular physiologist Nancy Carrasco named SEC Faculty Achievement Award winner
For her scholarship that has led to the development of new diagnostic and therapeutic approaches for thyroid cancer, Dr. Nancy Carrasco has been honored with a 2023 SEC Faculty Achievement Award. Read MoreMar 31, 2023
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Vanderbilt biochemists reveal the cause of Charcot-Marie-Tooth disease—too much of a good thing
Vanderbilt researchers—including Charles Sanders, associate dean for research and professor of biochemistry, and graduate student Justin Marinko—have illuminated the cause of Charcot-Marie-Tooth disease, putting them on the road to developing therapeutic approaches for the disease that affects one in 2,500 people. Read MoreOct 27, 2020
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A key to calcium signaling
Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles. Read MoreFeb 11, 2020
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Poster session Friday will feature work on next-gen vaccines
The computer-aided design and engineering of antibodies and vaccine candidates that can neutralize viral scourges like influenza and Ebola will be the topic of an Aug. 17 poster session presented by the Vanderbilt Center for Structural Biology and the Vanderbilt Vaccine Center. Read MoreAug 6, 2018
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New view of the heartbeat
Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias. Read MoreApr 6, 2018
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Noted neuroscientist Gouaux set for Discovery Lecture
Eric Gouaux, PhD, whose work has helped reveal the molecular mechanisms by which nerve cells communicate, will deliver the next Flexner Discovery Lecture Thursday, Feb. 22. Read MoreFeb 15, 2018
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DNA damage repair: molecular insights
Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer. Read MoreDec 5, 2017
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Repriming replication roadblocks
New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away. Read MoreJun 12, 2017
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A new mode of DNA repair
Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair. Read MoreApr 14, 2017
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Symposium on Modeling Immunity set for April 27
The Vanderbilt Center for Structural Biology and the Vanderbilt Vaccine Center invite you to attend the 2017 Symposium on Modeling Immunity April 27. The event will focus on modeling and designing antibodies. Read MoreApr 5, 2017
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Symposium on modeling immunity set for April 27
The 2017 Vanderbilt Symposium on Modeling Immunity will be held from 1 to 4:30 p.m. Thursday, April 27, in room 1220 MRB III. Read MoreMar 30, 2017
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Team identifies ‘switch’ involved in DNA replication
DNA replication is an extraordinarily complex multi-step process that makes copies of the body’s genetic blueprint. It is necessary for growth and essential to life. Now researchers at the California Institute of Technology (Caltech) and Vanderbilt University have found evidence that one of those steps may involve the telephone-like transmission of electrical signals regulated by a chemical “switch.” Read MoreFeb 23, 2017
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Transcription factor evolution
Vanderbilt researchers have discovered a novel model of evolution for factors that control gene expression. Read MoreAug 11, 2016
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How strep grabs on to platelets
New structural details of the binding of the bacterium Streptococcus sanguinis to platelets may offer new therapeutics for life-threatening cardiovascular infections. Read MoreApr 20, 2016
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Dynamics of a drug resistance transporter
Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance. Read MoreFeb 5, 2016
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New class of DNA repair enzyme discovered
A new class of DNA repair enzyme has been discovered which demonstrates that a much broader range of damage can be removed from the double helix in ways that biologists did not think were possible. Read MoreOct 29, 2015
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Study sheds light on crucial DNA binding protein
Researchers at Vanderbilt University have established the molecular basis for the function of Replication Protein A (RPA), a DNA binding protein that is a crucial “scaffold” for genome replication, response to damage and repair. Read MoreJul 30, 2015
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How to trick a wily virus
Vanderbilt investigators have discovered how human antibodies induced during testing of an experimental “bird flu” vaccine kill the virus. Read MoreJul 24, 2015
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Study reveals how protein helps cells tolerate DNA damage
Vanderbilt and Stanford investigators have discovered how a protein that's part of the DNA replication "machinery" helps cells tolerate DNA damage. Read MoreJul 16, 2015
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Center for Structural Biology symposium to feature stellar lineup
The Vanderbilt University Department of Biochemistry will host a two-day symposium March 6-7 to honor the 60th birthday of Walter Chazin, Ph.D., director of the Center for Structural Biology. Read MoreFeb 26, 2015