School Of Medicine Basic Sciences

Vanderbilt Basic Sciences will host a Mental Health and Wellness Summit on Tuesday, March 17, featuring keynote addresses for faculty and staff and for graduate students and postdoctoral scholars by Sharon Milgram, director of the National Institutes of Health Office of Intramural Training and Education. Read More

Jennifer Sucre and colleagues have discovered a factor that contributes to the pathological changes of bronchopulmonary dysplasia, the most common complication of preterm birth. Read More

Erin Calipari, Kelly Haws and Marybeth Shinn have been selected as Global Voices Fellows for the fall 2020 semester. Read More

Roger Colbran and colleagues have discovered new molecular details about the function of an enzyme with a key role in shaping learning and memory. Read More

A disease-associated mutation in a transporter protein causes cells to increase energy production, as if they are starving, Vanderbilt researchers have discovered. Read More

Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles. Read More

Stanley Cohen, a legendary Vanderbilt University biochemist who was awarded the Nobel Prize for the discovery of epidermal growth factor and its receptor, died on Feb. 5 at the age of 97. Read More

Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation. Read More

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis. Read More

A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report. Read More

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms. Read More

D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics. Read More

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy. Read More

To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction. Read More

The Enabling Innovation Initiative presents Kayla Graff, CEO and co-founder of SweetBio, who will discuss “Million Dollar Lessons: Attracting Capital to Fuel Your Biotech/Scientific Startup” on Friday, Dec. 13, beginning at 2 p.m. in Light Hall, Room 512. Read More

Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions. Read More

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes. Read More

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells. Read More

Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders. Read More

Reginald Cannady, a postdoctoral research fellow at the Medical University of South Carolina, will discuss “Probing Novel Targets to Reduce Heavy Drinking in Models of Alcohol Use Disorder” at 4 p.m. Tuesday, Nov. 12, in Light Hall, Room 512, as part of the Discovery Science Emerging Scholars Lecture Series. Read More