Schizophrenia
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Brain circuitry in psychosis
Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions. Read MoreAug 21, 2015
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Signals of schizophrenia
Vanderbilt researchers have discovered a possible molecular mechanism of schizophrenia that could lead to new treatments for the disorder. Read MoreJul 9, 2015
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A little jolt helps the brain get back on track
Applying mild electrical stimulation to an area of the brain associated with cognitive control helps people with schizophrenia to recognize errors and adjust their behavior to avoid them. Read MoreJul 8, 2015
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A view of brain function in disease
Vanderbilt investigators report the first use of a specialized type of MRI to study the hippocampus in patients with schizophrenia. Read MoreJun 16, 2015
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Findings reveal new target in quest to ease schizophrenia
Vanderbilt University researchers have uncovered a surprising finding that could lead to the development of new, more effective therapies for schizophrenia, which affects more than 2 million Americans. Read MoreMay 7, 2015
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Multi-sensory processing model explores autism, schizophrenia
There is growing evidence that disorders such as autism and schizophrenia involve deficits in what is called “multi-sensory processing,” the ability of the brain to properly integrate information coming in through the eyes, ears and other senses. Read MoreMar 19, 2015
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Grant spurs schizophrenia research
Vanderbilt University is partnering with the William K. Warren Foundation of Tulsa, Oklahoma, on research aimed at improving the treatment of schizophrenia and other forms of serious mental illness. Read MoreFeb 12, 2015
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Hazy definition may hamper catatonia care
Catatonia, a syndrome characterized by muscular rigidity and a trance-like mental stupor, can at times manifest with great excitement and confusion. And while it is often associated with schizophrenia, it can present in patients with either medical or psychiatric conditions. For this reason, the condition has often confused clinicians. Read MoreFeb 12, 2015
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New view of dopamine heteromers
Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist. Read MoreJan 23, 2015
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Family’s gift bolsters schizophrenia research, treatment
A “transformational” $6.4 million gift from Dallas couple Donald Test Jr., and his wife, Charlotte, who have a very personal connection to the devastating disease of schizophrenia, is supporting Vanderbilt Department of Psychiatry research and treatment into schizophrenia and related disorders. Read MoreDec 18, 2014
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VU study reveals shared pathways in psychiatric disorders
Schizophrenia and bipolar disorder share common genetic underpinnings. Vanderbilt researchers combined high-resolution gene expression studies with gene association data to reveal signaling pathways linked to schizophrenia and bipolar disorder. Read MoreSep 18, 2014
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Schizophrenia ‘switches’ discovered
Drugs developed at Vanderbilt could provide a new way to treat schizophrenia in a personalized way. Read MoreSep 12, 2014
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Brain mapping confirms patients with schizophrenia have impaired ability to imitate
A brain-mapping study of patients with schizophrenia has found that areas associated with the ability to imitate are impaired, providing new support for the theory that deficits in this basic cognitive skill may underlie the profound difficulty with social interactions that characterize the disorder. Read MoreMar 14, 2014
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‘Missing link’ may spur new brain disorder drugs
Researchers at the Scripps Research Institute in San Diego and Vanderbilt University have discovered a “missing link” in the structure of a transmembrane receptor that could lead to new treatments for autism, schizophrenia, Parkinson’s disease and Alzheimer’s disease. Read MoreMar 13, 2014
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Vanderbilt study reveals senses of sight and sound separated in children with autism
Children with autism spectrum disorders have trouble integrating simultaneous information from their eyes and their ears--as if they experience the world like a badly-dubbed movie. Read MoreJan 14, 2014
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Transporter linked to autism risk
Vanderbilt University investigators for the first time have linked a non-inherited, de novo mutation in the dopamine transporter to autism spectrum disorder (ASD). Read MoreSep 19, 2013
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Nobel in Chemistry reveals VU ties that bind
Several Vanderbilt researchers have collaborated with this year's Nobel Chemistry winners. Read MoreOct 18, 2012
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Insights for neuroscience drug discovery
When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects. Read MoreJul 17, 2012
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Perfect timing for sensory processing
Identification of brain regions involved in processing sights and sounds may offer insights into disorders like autism and dyslexia. Read MoreMay 11, 2012
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Next My Health Chat to explore ‘Discoveries in Neuroscience’ May 16
Reid Thompson talks with Lola Chambless in the neurosurgery OR. (Anne Rayner/VUMC) The May program for My Health Chat will be the fascinating field of neuroscience. Panelists will be Reid Thompson, chair of neurosurgery and director of the Vanderbilt Brain Tumor Center, and Jeff Conn,… Read MoreMay 1, 2012